Feasibility and impact of haplogroup matching for mitochondrial replacement treatment

Mitochondrial replacement technology (MRT) aims to reduce the risk of serious disease in children born to women who carry pathogenic mitochondrial DNA (mtDNA) variants. By transplanting nuclear genomes from eggs of an affected woman to enucleated eggs from an unaffected donor, MRT creates new combin...

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Detalles Bibliográficos
Autores principales: Takeda, Yuko, Hyslop, Louise, Choudhary, Meenakshi, Robertson, Fiona, Pyle, Angela, Wilson, Ian, Santibanez‐Koref, Mauro, Turnbull, Douglass, Herbert, Mary, Hudson, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Exploratory Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561356/
https://www.ncbi.nlm.nih.gov/pubmed/37589175
http://dx.doi.org/10.15252/embr.202154540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561356/
https://www.ncbi.nlm.nih.gov/pubmed/37589175
http://dx.doi.org/10.15252/embr.202154540

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