Cargando…

Feasibility and impact of haplogroup matching for mitochondrial replacement treatment

Mitochondrial replacement technology (MRT) aims to reduce the risk of serious disease in children born to women who carry pathogenic mitochondrial DNA (mtDNA) variants. By transplanting nuclear genomes from eggs of an affected woman to enucleated eggs from an unaffected donor, MRT creates new combin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takeda, Yuko, Hyslop, Louise, Choudhary, Meenakshi, Robertson, Fiona, Pyle, Angela, Wilson, Ian, Santibanez‐Koref, Mauro, Turnbull, Douglass, Herbert, Mary, Hudson, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Exploratory Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561356/ https://www.ncbi.nlm.nih.gov/pubmed/37589175 http://dx.doi.org/10.15252/embr.202154540

Ejemplares similares

Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution
por: Santibanez-Koref, Mauro, et al.
Publicado: (2019)

How do stroke survivors and their caregivers manage post-stroke fatigue? A qualitative study
por: Ablewhite, Joanne, et al.
Publicado: (2022)

Circulating cell-free mitochondrial DNA levels in Parkinson’s disease are influenced by treatment
por: Lowes, Hannah, et al.
Publicado: (2020)

Physical activity in patients with venous leg ulcer – between engagement and avoidance. A patient perspective
por: Roaldsen, Kirsti Skavberg, et al.
Publicado: (2011)

Trial participants’ experiences of early enhanced speech and language therapy after stroke compared with employed visitor support: a qualitative study nested within a randomized controlled trial
por: Young, Alys, et al.
Publicado: (2013)

Falls in people with multiple sclerosis: experiences of 115 fall situations
por: Carling, Anna, et al.
Publicado: (2017)

The impact of self-perceived limitations, stigma and sense of coherence on quality of life in multiple sclerosis patients: results of a cross-sectional study
por: Broersma, Feddrik, et al.
Publicado: (2017)

A scoping review of the needs of children and other family members after a child’s traumatic injury
por: Jones, Samantha, et al.
Publicado: (2017)

Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
por: Clarke, David J, et al.
Publicado: (2018)

What influences decisions about ongoing stroke rehabilitation for patients with pre-existing dementia or cognitive impairment: a qualitative study?
por: Longley, Verity, et al.
Publicado: (2018)

The role of meaning in life: mediating the effects of perceived knowledge of stroke on depression and life satisfaction among stroke survivors
por: Chow, Esther OW
Publicado: (2017)

What factors affect clinical decision-making about access to stroke rehabilitation? A systematic review
por: Longley, Verity, et al.
Publicado: (2018)

A qualitative study of patient-centered goal-setting in geriatric rehabilitation: patient and professional perspectives
por: van Seben, Rosanne, et al.
Publicado: (2018)

Does pre-existing cognitive impairment impact on amount of stroke rehabilitation received? An observational cohort study
por: Longley, Verity, et al.
Publicado: (2019)

Stroke patients’ and non-professional coaches’ experiences with home-based constraint-induced movement therapy: a qualitative study
por: Stark, Anne, et al.
Publicado: (2019)

What environmental factors influence resumption of valued activities post stroke: a systematic review of qualitative and quantitative findings
por: Jellema, Sandra, et al.
Publicado: (2016)

Where have all the pilot studies gone? A follow-up on 30 years of pilot studies in Clinical Rehabilitation
por: Kaur, Navaldeep, et al.
Publicado: (2017)

Negotiating identity and self-image: perceptions of falls in ambulatory individuals with spinal cord injury – a qualitative study
por: Jørgensen, Vivien, et al.
Publicado: (2016)

Co-constructing engagement in stroke rehabilitation: a qualitative study exploring how practitioner engagement can influence patient engagement
por: Bright, Felicity AS, et al.
Publicado: (2017)

How do patients pass through stroke services? Identifying stroke care pathways using national audit data
por: Gittins, Matthew, et al.
Publicado: (2020)

Factors influencing the amount of therapy received during inpatient stroke care: an analysis of data from the UK Sentinel Stroke National Audit Programme
por: Gittins, Matthew, et al.
Publicado: (2020)

The self-assessment INTERMED predicts healthcare and social costs of orthopaedic trauma patients with persistent impairments
por: Burrus, Cyrille, et al.
Publicado: (2020)

Evaluation of the enhanced upper limb therapy programme within the Robot-Assisted Training for the Upper Limb after Stroke trial: descriptive analysis of intervention fidelity, goal selection and goal achievement
por: Bosomworth, Helen, et al.
Publicado: (2020)

Objectively-assessed physical activity and self-reported activity pacing in adults with multiple sclerosis: A pilot study
por: Abonie, Ulric S, et al.
Publicado: (2021)

Survivors of Hell: Resilience Amongst Unaccompanied Minor Refugees and Implications for Treatment- a Narrative Review
por: Rodriguez, Irene Mateos, et al.
Publicado: (2021)

Setting meaningful goals in rehabilitation: A qualitative study on the experiences of clients and clinicians in working with a practical tool
por: Littooij, Elsbeth, et al.
Publicado: (2021)

Early childhood education and care (ECEC) during COVID‐19 boosts growth in language and executive function
por: Davies, Catherine, et al.
Publicado: (2021)

Inhibitory control and problem solving in early childhood: Exploring the burdens and benefits of high self‐control
por: Hendry, Alexandra, et al.
Publicado: (2022)

Physical activity enjoyment, exercise motivation, and physical activity in patients with heart failure: A mediation analysis
por: Klompstra, Leonie, et al.
Publicado: (2022)

The Better By Moving study: A multifaceted intervention to improve physical activity in adults during hospital stay
por: Geelen, Sven JG, et al.
Publicado: (2022)

Impaired activation of transposable elements in SARS‐CoV‐2 infection
por: Sorek, Matan, et al.
Publicado: (2022)

Embitterment – Conception of a Potential Moderator to Dysfunctional and Aggressive Behaviour in Children and Adolescents
por: Balder, Tim, et al.
Publicado: (2021)

Prolonged disorders of consciousness: A response to a “critical evaluation of the new UK guidelines.”
por: Wade, Derick T, et al.
Publicado: (2022)

Barriers and facilitators related to self-management of shoulder pain: a systematic review and qualitative synthesis
por: O’Shea, Aidan, et al.
Publicado: (2022)

Facilitators and barriers to patient-centred goal-setting in rehabilitation: A scoping review
por: Crawford, L., et al.
Publicado: (2022)

Do people with musculoskeletal pain differ from healthy cohorts in terms of global measures of strength? A systematic review and meta-analysis
por: Verdini, Enrico, et al.
Publicado: (2022)

Mitigating Rural Adolescent Trauma: Remote Delivery of a Trauma-Informed Yoga Intervention During COVID-19
por: Davis, Lauren, et al.
Publicado: (2022)

Effect of COVID-19 Pandemic Response and Parental Adverse Childhood Experiences on Child Health and Well-Being
por: Arowolo, Tolu, et al.
Publicado: (2023)

Exemplary post-discharge stroke rehabilitation programs: A multiple case study
por: Egan, Mary, et al.
Publicado: (2022)

A systematic review of the determinants of implementation of a locomotor training program using a powered exoskeleton for individuals with a spinal cord injury
por: Charette, Caroline, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8duf15mgfs4gacv1bsam7l37tp