Single-cell RNA sequencing of neurofibromas reveals a tumor microenvironment favorable for neural regeneration and immune suppression in a neurofibromatosis type 1 porcine model

Neurofibromatosis Type 1 (NF1) is one of the most common genetically inherited disorders that affects 1 in 3000 children annually. Clinical manifestations vary widely but nearly always include the development of cutaneous, plexiform and diffuse neurofibromas that are managed over many years. Recent...

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Detalles Bibliográficos
Autores principales: McLean, Dalton T., Meudt, Jennifer J., Lopez Rivera, Loren D., Schomberg, Dominic T., Pavelec, Derek M., Duellman, Tyler T., Buehler, Darya G., Schwartz, Patrick B., Graham, Melissa, Lee, Laura M., Graff, Keri D., Reichert, Jamie L., Bon-Durant, Sandra S., Konsitzke, Charles M., Ronnekleiv-Kelly, Sean M., Shanmuganayagam, Dhanansayan, Rubinstein, C. Dustin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561395/
https://www.ncbi.nlm.nih.gov/pubmed/37817770
http://dx.doi.org/10.3389/fonc.2023.1253659

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