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The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles
BACKGROUND: The safety and efficacy of 17-gauge needles used in CT-guided percutaneous cryoablation for lung nodules were explored in this study. The purpose of the study was to compare the findings with earlier research and multi-center clinical trials that used various needle sizes. METHODS: Betwe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561456/ https://www.ncbi.nlm.nih.gov/pubmed/37814246 http://dx.doi.org/10.1186/s12880-023-01110-6 |
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author | Lin, Wei-Chan Chen, Po-Ju Yim, Shelly Wang, Hsueh-Han Liao, Pen-An Tai, Chia-Yu Yen, Ming-Hong |
author_facet | Lin, Wei-Chan Chen, Po-Ju Yim, Shelly Wang, Hsueh-Han Liao, Pen-An Tai, Chia-Yu Yen, Ming-Hong |
author_sort | Lin, Wei-Chan |
collection | PubMed |
description | BACKGROUND: The safety and efficacy of 17-gauge needles used in CT-guided percutaneous cryoablation for lung nodules were explored in this study. The purpose of the study was to compare the findings with earlier research and multi-center clinical trials that used various needle sizes. METHODS: Between 2016 and 2020, a retrospective study was conducted with approval from the institutional review board. A total of 41 patients were enrolled, and 71 lung nodules were treated in 63 cryoablation procedures using local anesthesia. Complication rates were recorded, and overall survival rates as well as tumor progression-free rates were calculated using the Kaplan-Meier method. RESULTS: Self-limited hemoptysis was caused by 12.9% of the procedures, and drainage was required for pneumothoraces resulting from 11.3% of them. The overall survival rates at one, two, three, and four years were 97%, 94%, 82%, and 67%, respectively. The tumor progression-free rates at one, two, three, and four years were 86.2%, 77%, 74%, and 65%, respectively. CONCLUSION: Cryoablation for lung nodules using 17-Gauge needles can achieve similar rates of survival and tumor control rates, similar or even lower complication rates as compared with other studies and multi-center trials using mixed sized needles. |
format | Online Article Text |
id | pubmed-10561456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105614562023-10-10 The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles Lin, Wei-Chan Chen, Po-Ju Yim, Shelly Wang, Hsueh-Han Liao, Pen-An Tai, Chia-Yu Yen, Ming-Hong BMC Med Imaging Research BACKGROUND: The safety and efficacy of 17-gauge needles used in CT-guided percutaneous cryoablation for lung nodules were explored in this study. The purpose of the study was to compare the findings with earlier research and multi-center clinical trials that used various needle sizes. METHODS: Between 2016 and 2020, a retrospective study was conducted with approval from the institutional review board. A total of 41 patients were enrolled, and 71 lung nodules were treated in 63 cryoablation procedures using local anesthesia. Complication rates were recorded, and overall survival rates as well as tumor progression-free rates were calculated using the Kaplan-Meier method. RESULTS: Self-limited hemoptysis was caused by 12.9% of the procedures, and drainage was required for pneumothoraces resulting from 11.3% of them. The overall survival rates at one, two, three, and four years were 97%, 94%, 82%, and 67%, respectively. The tumor progression-free rates at one, two, three, and four years were 86.2%, 77%, 74%, and 65%, respectively. CONCLUSION: Cryoablation for lung nodules using 17-Gauge needles can achieve similar rates of survival and tumor control rates, similar or even lower complication rates as compared with other studies and multi-center trials using mixed sized needles. BioMed Central 2023-10-09 /pmc/articles/PMC10561456/ /pubmed/37814246 http://dx.doi.org/10.1186/s12880-023-01110-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Lin, Wei-Chan Chen, Po-Ju Yim, Shelly Wang, Hsueh-Han Liao, Pen-An Tai, Chia-Yu Yen, Ming-Hong The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title | The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title_full | The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title_fullStr | The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title_full_unstemmed | The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title_short | The safety and response of CT guided percutaneous cryoablation for lung nodules by 17-gauge needles |
title_sort | safety and response of ct guided percutaneous cryoablation for lung nodules by 17-gauge needles |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561456/ https://www.ncbi.nlm.nih.gov/pubmed/37814246 http://dx.doi.org/10.1186/s12880-023-01110-6 |
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