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Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values

The musculoskeletal system is important for balancing metabolic activity and maintaining health. Recent studies have shown that distortions in homeostasis of the intestinal microbiota are correlated with or may even contribute to abnormalities in musculoskeletal system function. Research has also sh...

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Autores principales: Wang, Yu, Li, Yusheng, Bo, Lin, Zhou, Enyuan, Chen, Yanyan, Naranmandakh, Shinen, Xie, Wenqing, Ru, Qin, Chen, Lin, Zhu, Zhaohua, Ding, Changhai, Wu, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561578/
https://www.ncbi.nlm.nih.gov/pubmed/37800576
http://dx.doi.org/10.1080/19490976.2023.2263207
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author Wang, Yu
Li, Yusheng
Bo, Lin
Zhou, Enyuan
Chen, Yanyan
Naranmandakh, Shinen
Xie, Wenqing
Ru, Qin
Chen, Lin
Zhu, Zhaohua
Ding, Changhai
Wu, Yuxiang
author_facet Wang, Yu
Li, Yusheng
Bo, Lin
Zhou, Enyuan
Chen, Yanyan
Naranmandakh, Shinen
Xie, Wenqing
Ru, Qin
Chen, Lin
Zhu, Zhaohua
Ding, Changhai
Wu, Yuxiang
author_sort Wang, Yu
collection PubMed
description The musculoskeletal system is important for balancing metabolic activity and maintaining health. Recent studies have shown that distortions in homeostasis of the intestinal microbiota are correlated with or may even contribute to abnormalities in musculoskeletal system function. Research has also shown that the intestinal flora and its secondary metabolites can impact the musculoskeletal system by regulating various phenomena, such as inflammation and immune and metabolic activities. Most of the existing literature supports that reasonable nutritional intervention helps to improve and maintain the homeostasis of intestinal microbiota, and may have a positive impact on musculoskeletal health. The purpose of organizing, summarizing and discussing the existing literature is to explore whether the intervention methods, including nutritional supplement and moderate exercise, can affect the muscle and bone health by regulating the microecology of the intestinal flora. More in-depth efficacy verification experiments will be helpful for clinical applications.
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spelling pubmed-105615782023-10-10 Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values Wang, Yu Li, Yusheng Bo, Lin Zhou, Enyuan Chen, Yanyan Naranmandakh, Shinen Xie, Wenqing Ru, Qin Chen, Lin Zhu, Zhaohua Ding, Changhai Wu, Yuxiang Gut Microbes Review The musculoskeletal system is important for balancing metabolic activity and maintaining health. Recent studies have shown that distortions in homeostasis of the intestinal microbiota are correlated with or may even contribute to abnormalities in musculoskeletal system function. Research has also shown that the intestinal flora and its secondary metabolites can impact the musculoskeletal system by regulating various phenomena, such as inflammation and immune and metabolic activities. Most of the existing literature supports that reasonable nutritional intervention helps to improve and maintain the homeostasis of intestinal microbiota, and may have a positive impact on musculoskeletal health. The purpose of organizing, summarizing and discussing the existing literature is to explore whether the intervention methods, including nutritional supplement and moderate exercise, can affect the muscle and bone health by regulating the microecology of the intestinal flora. More in-depth efficacy verification experiments will be helpful for clinical applications. Taylor & Francis 2023-10-06 /pmc/articles/PMC10561578/ /pubmed/37800576 http://dx.doi.org/10.1080/19490976.2023.2263207 Text en © 2023 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
spellingShingle Review
Wang, Yu
Li, Yusheng
Bo, Lin
Zhou, Enyuan
Chen, Yanyan
Naranmandakh, Shinen
Xie, Wenqing
Ru, Qin
Chen, Lin
Zhu, Zhaohua
Ding, Changhai
Wu, Yuxiang
Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title_full Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title_fullStr Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title_full_unstemmed Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title_short Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
title_sort progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561578/
https://www.ncbi.nlm.nih.gov/pubmed/37800576
http://dx.doi.org/10.1080/19490976.2023.2263207
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