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Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords

Magnetic resonance imaging is currently the gold standard for the evaluation of spinal cord injuries. Automatic analysis of these injuries is however challenging, as MRI resolutions vary for different planes of analysis and physiological features are often distorted around these injuries. This study...

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Autores principales: Masse‐Gignac, Nicolas, Flórez‐Jiménez, Salomón, Mac‐Thiong, Jean‐Marc, Duong, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562020/
https://www.ncbi.nlm.nih.gov/pubmed/37735825
http://dx.doi.org/10.1002/acm2.14123
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author Masse‐Gignac, Nicolas
Flórez‐Jiménez, Salomón
Mac‐Thiong, Jean‐Marc
Duong, Luc
author_facet Masse‐Gignac, Nicolas
Flórez‐Jiménez, Salomón
Mac‐Thiong, Jean‐Marc
Duong, Luc
author_sort Masse‐Gignac, Nicolas
collection PubMed
description Magnetic resonance imaging is currently the gold standard for the evaluation of spinal cord injuries. Automatic analysis of these injuries is however challenging, as MRI resolutions vary for different planes of analysis and physiological features are often distorted around these injuries. This study proposes a new CNN‐based segmentation method in which information is exchanged between two networks analyzing the scans from different planes. Our aim was to develop a robust method for automatic segmentation of the spinal cord in patients having suffered traumatic injuries. The database consisted of 106 sagittal MRI scans from 94 patients with traumatic spinal cord injuries. Our method used an innovative approach where the scans were analyzed in series under the axial and sagittal plane by two different convolutional networks. The results were compared with those of Deepseg 2D from the Spinal Cord Toolbox (SCT), which was taken as state‐of‐the‐art. Comparisons were evaluated using K‐Fold cross‐validation combined with statistical t‐test results on separate test data. Our method achieved significantly better results than Deepseg 2D, with an average Dice coefficient of 0.95 against 0.88 for Deepseg 2D (p <0.001). Other metrics were also used to compare the segmentations, all of which showed significantly better results for our approach. In this study, we introduce a robust method for spinal cord segmentation which is capable of adequately segmenting spinal cords affected by traumatic injuries, improving upon the methods contained in SCT.
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spelling pubmed-105620202023-10-10 Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords Masse‐Gignac, Nicolas Flórez‐Jiménez, Salomón Mac‐Thiong, Jean‐Marc Duong, Luc J Appl Clin Med Phys Medical Imaging Magnetic resonance imaging is currently the gold standard for the evaluation of spinal cord injuries. Automatic analysis of these injuries is however challenging, as MRI resolutions vary for different planes of analysis and physiological features are often distorted around these injuries. This study proposes a new CNN‐based segmentation method in which information is exchanged between two networks analyzing the scans from different planes. Our aim was to develop a robust method for automatic segmentation of the spinal cord in patients having suffered traumatic injuries. The database consisted of 106 sagittal MRI scans from 94 patients with traumatic spinal cord injuries. Our method used an innovative approach where the scans were analyzed in series under the axial and sagittal plane by two different convolutional networks. The results were compared with those of Deepseg 2D from the Spinal Cord Toolbox (SCT), which was taken as state‐of‐the‐art. Comparisons were evaluated using K‐Fold cross‐validation combined with statistical t‐test results on separate test data. Our method achieved significantly better results than Deepseg 2D, with an average Dice coefficient of 0.95 against 0.88 for Deepseg 2D (p <0.001). Other metrics were also used to compare the segmentations, all of which showed significantly better results for our approach. In this study, we introduce a robust method for spinal cord segmentation which is capable of adequately segmenting spinal cords affected by traumatic injuries, improving upon the methods contained in SCT. John Wiley and Sons Inc. 2023-09-21 /pmc/articles/PMC10562020/ /pubmed/37735825 http://dx.doi.org/10.1002/acm2.14123 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics is published by Wiley Periodicals, Inc. on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Medical Imaging
Masse‐Gignac, Nicolas
Flórez‐Jiménez, Salomón
Mac‐Thiong, Jean‐Marc
Duong, Luc
Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title_full Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title_fullStr Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title_full_unstemmed Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title_short Attention‐gated U‐Net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
title_sort attention‐gated u‐net networks for simultaneous axial/sagittal planes segmentation of injured spinal cords
topic Medical Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562020/
https://www.ncbi.nlm.nih.gov/pubmed/37735825
http://dx.doi.org/10.1002/acm2.14123
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