Cargando…

The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms

To evaluate the dosimetric impact of titanium implants in spine SBRT using four dose calculation algorithms. Twenty patients with titanium implants in the spine treated with SBRT without density override (DO) were selected. The clinical plan for each patient was created in Pinnacle and subsequently...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chieh‐Wen, Cho, Young‐Bin, Magnelli, Anthony, Angelov, Lilyana, Balagamwala, Ehsan H., Chao, Samuel T., Xia, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562029/
https://www.ncbi.nlm.nih.gov/pubmed/37540084
http://dx.doi.org/10.1002/acm2.14070
_version_ 1785118037921234944
author Liu, Chieh‐Wen
Cho, Young‐Bin
Magnelli, Anthony
Angelov, Lilyana
Balagamwala, Ehsan H.
Chao, Samuel T.
Xia, Ping
author_facet Liu, Chieh‐Wen
Cho, Young‐Bin
Magnelli, Anthony
Angelov, Lilyana
Balagamwala, Ehsan H.
Chao, Samuel T.
Xia, Ping
author_sort Liu, Chieh‐Wen
collection PubMed
description To evaluate the dosimetric impact of titanium implants in spine SBRT using four dose calculation algorithms. Twenty patients with titanium implants in the spine treated with SBRT without density override (DO) were selected. The clinical plan for each patient was created in Pinnacle and subsequently imported into Eclipse (AAA and AcurosXB) and Raystation (CC) for dose evaluation with and without DO to the titanium implant. We renormalized all plans such that 90% of the tumor volume received the prescription dose and subsequently evaluated the following dose metrics: (1) the maximum dose to 0.03 cc (Dmax), dose to 99% (D99%) and 90% (D90%) of the tumor volume; (2) Dmax and volumetric metrics of the spinal cord. For the same algorithm, plans with and without DO had similar dose distributions. Differences in Dmax, D99% and D90% of the tumor were on average <2% with slightly larger variations up to 5.58% in Dmax using AcurosXB. Dmax of the spinal cord for plans calculated with DO increased but the differences were clinically insignificant for all algorithms (mean: 0.36% ± 0.7%). Comparing to the clinical plans, the relative differences for all algorithms had an average of 1.73% (−10.36%–13.21%) for the tumor metrics and −0.93% (−9.87%–10.95%) for Dmax of the spinal cord. A few cases with small tumor and spinal cord volumes, dose differences of >10% in both D99% and Dmax of the tumor, and Dmax of the spinal cord were observed. For all algorithms, the presence of titanium implants in the spine for most patients had minimal impact on dose distributions with and without DO. For the same plan calculated with different algorithms, larger differences in volumetric metrics of >10% could be observed, impacted by dose gradient at the plan normalization volume, tumor volumes, plan complexity, and partial voxel volume interpolation.
format Online
Article
Text
id pubmed-10562029
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-105620292023-10-10 The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms Liu, Chieh‐Wen Cho, Young‐Bin Magnelli, Anthony Angelov, Lilyana Balagamwala, Ehsan H. Chao, Samuel T. Xia, Ping J Appl Clin Med Phys Radiation Oncology Physics To evaluate the dosimetric impact of titanium implants in spine SBRT using four dose calculation algorithms. Twenty patients with titanium implants in the spine treated with SBRT without density override (DO) were selected. The clinical plan for each patient was created in Pinnacle and subsequently imported into Eclipse (AAA and AcurosXB) and Raystation (CC) for dose evaluation with and without DO to the titanium implant. We renormalized all plans such that 90% of the tumor volume received the prescription dose and subsequently evaluated the following dose metrics: (1) the maximum dose to 0.03 cc (Dmax), dose to 99% (D99%) and 90% (D90%) of the tumor volume; (2) Dmax and volumetric metrics of the spinal cord. For the same algorithm, plans with and without DO had similar dose distributions. Differences in Dmax, D99% and D90% of the tumor were on average <2% with slightly larger variations up to 5.58% in Dmax using AcurosXB. Dmax of the spinal cord for plans calculated with DO increased but the differences were clinically insignificant for all algorithms (mean: 0.36% ± 0.7%). Comparing to the clinical plans, the relative differences for all algorithms had an average of 1.73% (−10.36%–13.21%) for the tumor metrics and −0.93% (−9.87%–10.95%) for Dmax of the spinal cord. A few cases with small tumor and spinal cord volumes, dose differences of >10% in both D99% and Dmax of the tumor, and Dmax of the spinal cord were observed. For all algorithms, the presence of titanium implants in the spine for most patients had minimal impact on dose distributions with and without DO. For the same plan calculated with different algorithms, larger differences in volumetric metrics of >10% could be observed, impacted by dose gradient at the plan normalization volume, tumor volumes, plan complexity, and partial voxel volume interpolation. John Wiley and Sons Inc. 2023-08-04 /pmc/articles/PMC10562029/ /pubmed/37540084 http://dx.doi.org/10.1002/acm2.14070 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Liu, Chieh‐Wen
Cho, Young‐Bin
Magnelli, Anthony
Angelov, Lilyana
Balagamwala, Ehsan H.
Chao, Samuel T.
Xia, Ping
The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title_full The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title_fullStr The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title_full_unstemmed The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title_short The dosimetric impact of titanium implants in spinal SBRT using four commercial treatment planning algorithms
title_sort dosimetric impact of titanium implants in spinal sbrt using four commercial treatment planning algorithms
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562029/
https://www.ncbi.nlm.nih.gov/pubmed/37540084
http://dx.doi.org/10.1002/acm2.14070
work_keys_str_mv AT liuchiehwen thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT choyoungbin thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT magnellianthony thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT angelovlilyana thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT balagamwalaehsanh thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT chaosamuelt thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT xiaping thedosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT liuchiehwen dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT choyoungbin dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT magnellianthony dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT angelovlilyana dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT balagamwalaehsanh dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT chaosamuelt dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms
AT xiaping dosimetricimpactoftitaniumimplantsinspinalsbrtusingfourcommercialtreatmentplanningalgorithms