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Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion

PURPOSE: The purpose of this study is to calculate volume averaging correction factors for detectors used in the dosimetry of Gamma Knife's narrow photon beams, and to determine the impact of volume averaging on the field output correction factor. METHODS: Simulations of different Gamma Knife f...

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Autores principales: Šegedin, Nikola, Hršak, Hrvoje, Babić, Sanja Dolanski, Jurković, Slaven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562043/
https://www.ncbi.nlm.nih.gov/pubmed/37632162
http://dx.doi.org/10.1002/acm2.14109
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author Šegedin, Nikola
Hršak, Hrvoje
Babić, Sanja Dolanski
Jurković, Slaven
author_facet Šegedin, Nikola
Hršak, Hrvoje
Babić, Sanja Dolanski
Jurković, Slaven
author_sort Šegedin, Nikola
collection PubMed
description PURPOSE: The purpose of this study is to calculate volume averaging correction factors for detectors used in the dosimetry of Gamma Knife's narrow photon beams, and to determine the impact of volume averaging on the field output correction factor. METHODS: Simulations of different Gamma Knife fields were done using elliptical dose model formalism with newly introduced fit functions. To determine volume averaging correction factors a calculation of the absorbed dose over the volume of the detector was performed. The elliptical dose model was tested with respect to absorbed dose distribution for different volumes and compared with the calculations of Leksell GammaPlan v.11.3.1. RESULTS: The largest differences in absorbed dose calculated by the elliptical model and Leksell GammaPlan are 2.25%, 1.5%, and 0.6% for 16, 8, and 4 mm field sizes, respectively. Volume averaging correction factors were determined for six ionization chambers, five semiconductor detectors, a diamond, and two plastic scintillator detectors. In general, for all examined detectors the impact of volume averaging is more pronounced for smaller field sizes. All studied ionization chambers had a larger volume than other detectors, therefore the volume averaging correction factors for ionization chambers are larger for all investigated field sizes. Besides the fact that plastic scintillator detectors can be considered tissue‐equivalent, volume averaging correction factor should be applied. CONCLUSION: Volume averaging correction factors for different detectors are determined and suitable detectors for dosimetry of Gamma Knife's narrow photon beams are recommended. It is shown that volume averaging has a dominant contribution to a field output correction factor.
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spelling pubmed-105620432023-10-10 Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion Šegedin, Nikola Hršak, Hrvoje Babić, Sanja Dolanski Jurković, Slaven J Appl Clin Med Phys Radiation Measurements PURPOSE: The purpose of this study is to calculate volume averaging correction factors for detectors used in the dosimetry of Gamma Knife's narrow photon beams, and to determine the impact of volume averaging on the field output correction factor. METHODS: Simulations of different Gamma Knife fields were done using elliptical dose model formalism with newly introduced fit functions. To determine volume averaging correction factors a calculation of the absorbed dose over the volume of the detector was performed. The elliptical dose model was tested with respect to absorbed dose distribution for different volumes and compared with the calculations of Leksell GammaPlan v.11.3.1. RESULTS: The largest differences in absorbed dose calculated by the elliptical model and Leksell GammaPlan are 2.25%, 1.5%, and 0.6% for 16, 8, and 4 mm field sizes, respectively. Volume averaging correction factors were determined for six ionization chambers, five semiconductor detectors, a diamond, and two plastic scintillator detectors. In general, for all examined detectors the impact of volume averaging is more pronounced for smaller field sizes. All studied ionization chambers had a larger volume than other detectors, therefore the volume averaging correction factors for ionization chambers are larger for all investigated field sizes. Besides the fact that plastic scintillator detectors can be considered tissue‐equivalent, volume averaging correction factor should be applied. CONCLUSION: Volume averaging correction factors for different detectors are determined and suitable detectors for dosimetry of Gamma Knife's narrow photon beams are recommended. It is shown that volume averaging has a dominant contribution to a field output correction factor. John Wiley and Sons Inc. 2023-08-25 /pmc/articles/PMC10562043/ /pubmed/37632162 http://dx.doi.org/10.1002/acm2.14109 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Measurements
Šegedin, Nikola
Hršak, Hrvoje
Babić, Sanja Dolanski
Jurković, Slaven
Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title_full Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title_fullStr Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title_full_unstemmed Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title_short Determination of volume averaging correction factors using an elliptical absorbed dose model for Gamma Knife Perfexion
title_sort determination of volume averaging correction factors using an elliptical absorbed dose model for gamma knife perfexion
topic Radiation Measurements
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562043/
https://www.ncbi.nlm.nih.gov/pubmed/37632162
http://dx.doi.org/10.1002/acm2.14109
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