Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring aquaporin-2 levels via regulation of the silent information regulator 1 signaling pathway

BACKGROUND: Acute kidney injury (AKI) is a serious pathology that causes dysfunction in concentrating urine due to kidney damage, resulting in blood pressure dysregulation and increased levels of toxic metabolites. Dexpanthenol (DEX), a pantothenic acid analog, exhibits anti-inflammatory and anti-ap...

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Detalles Bibliográficos
Autores principales: Özden, Eyyüp Sabri, Aşcı, Halil, Büyükbayram, Halil İbrahim, Sevük, Mehmet Abdulkadir, İmeci, Orhan Berk, Doğan, Hatice Kübra, Özmen, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Anesthesiologists 2023
Materias:
Experimental Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562075/
https://www.ncbi.nlm.nih.gov/pubmed/37232072
http://dx.doi.org/10.4097/kja.23207

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