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Allogeneic tumor cell-derived extracellular vesicles stimulate CD8 T cell response in colorectal cancer

Most colorectal cancer (CRC) patients present with a microsatellite-stable phenotype, rendering them resistant to immune checkpoint inhibitors (ICIs). Among the contributors to ICI resistance, tumor-derived extracellular vesicles (TEVs) have emerged as critical players. Previously we demonstrated th...

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Detalles Bibliográficos
Autores principales: Gates, Travis J., Wangmo, Dechen, Zhao, Xianda, Subramanian, Subbaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562189/
https://www.ncbi.nlm.nih.gov/pubmed/37822487
http://dx.doi.org/10.1016/j.omto.2023.100727