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Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran

BACKGROUND: Asymptomatic malaria is a major challenge to be addressed in the implementation of the malaria elimination program. The main goal of the malaria surveillance system in the elimination phase is to identify reliably all the positive cases of malaria reliably (symptomatic and asymptomatic)...

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Autores principales: Hosseini, Zainab, Azizi, Kourosh, Moghadami, Mohsen, Hassaniazad, Mehdi, Shafiei, Reza, Rezaee, Elham, Turki, Habibollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562199/
https://www.ncbi.nlm.nih.gov/pubmed/37822760
http://dx.doi.org/10.18502/jad.v17i2.13618
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author Hosseini, Zainab
Azizi, Kourosh
Moghadami, Mohsen
Hassaniazad, Mehdi
Shafiei, Reza
Rezaee, Elham
Turki, Habibollah
author_facet Hosseini, Zainab
Azizi, Kourosh
Moghadami, Mohsen
Hassaniazad, Mehdi
Shafiei, Reza
Rezaee, Elham
Turki, Habibollah
author_sort Hosseini, Zainab
collection PubMed
description BACKGROUND: Asymptomatic malaria is a major challenge to be addressed in the implementation of the malaria elimination program. The main goal of the malaria surveillance system in the elimination phase is to identify reliably all the positive cases of malaria reliably (symptomatic and asymptomatic) in the shortest possible time. This study focused on the monitoring of asymptomatic malaria reservoirs in areas where local transmission had been previously established. METHODS: It was a case-study approach that was conducted in the Anarestan area. A total of 246 residents and immigrants living in the area at the age range of 4–60 years old were randomly selected to be tested for malaria by microscope, RDT, and nested-PCR techniques. The inclusion criterion for participants to be entered into the study was the absence of specific symptoms of malaria. Moreover, participants who have been taking antimalarials for the last month were excluded from the study. RESULTS: The results indicated no positive cases of asymptomatic malaria among the participants tested by all methods. CONCLUSION: The results of this study have shown that, without concerns for asymptomatic parasitic patients, a malaria elimination program has been successfully implemented within the studies area. In addition, the findings emphasized the existence of a strong malaria surveillance system in this area.
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spelling pubmed-105621992023-10-11 Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran Hosseini, Zainab Azizi, Kourosh Moghadami, Mohsen Hassaniazad, Mehdi Shafiei, Reza Rezaee, Elham Turki, Habibollah J Arthropod Borne Dis Original Article BACKGROUND: Asymptomatic malaria is a major challenge to be addressed in the implementation of the malaria elimination program. The main goal of the malaria surveillance system in the elimination phase is to identify reliably all the positive cases of malaria reliably (symptomatic and asymptomatic) in the shortest possible time. This study focused on the monitoring of asymptomatic malaria reservoirs in areas where local transmission had been previously established. METHODS: It was a case-study approach that was conducted in the Anarestan area. A total of 246 residents and immigrants living in the area at the age range of 4–60 years old were randomly selected to be tested for malaria by microscope, RDT, and nested-PCR techniques. The inclusion criterion for participants to be entered into the study was the absence of specific symptoms of malaria. Moreover, participants who have been taking antimalarials for the last month were excluded from the study. RESULTS: The results indicated no positive cases of asymptomatic malaria among the participants tested by all methods. CONCLUSION: The results of this study have shown that, without concerns for asymptomatic parasitic patients, a malaria elimination program has been successfully implemented within the studies area. In addition, the findings emphasized the existence of a strong malaria surveillance system in this area. Tehran University of Medical Sciences 2023-06-30 /pmc/articles/PMC10562199/ /pubmed/37822760 http://dx.doi.org/10.18502/jad.v17i2.13618 Text en Copyright © 2023 The Authors. Published by Tehran University of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Hosseini, Zainab
Azizi, Kourosh
Moghadami, Mohsen
Hassaniazad, Mehdi
Shafiei, Reza
Rezaee, Elham
Turki, Habibollah
Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title_full Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title_fullStr Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title_full_unstemmed Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title_short Absence of Asymptomatic Malaria Reservoirs in an Area with a Previous History of Local Malaria Transmission: A Successful Experience in Line with the Malaria Elimination Program in Iran
title_sort absence of asymptomatic malaria reservoirs in an area with a previous history of local malaria transmission: a successful experience in line with the malaria elimination program in iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562199/
https://www.ncbi.nlm.nih.gov/pubmed/37822760
http://dx.doi.org/10.18502/jad.v17i2.13618
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