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Snoring might be a warning sign for metabolic syndrome in nonobese Korean women

Metabolic syndrome (MetS) is an underlying cause of various diseases and is strongly associated with mortality. In particular, it has been steadily increasing along with changes in diet and lifestyle habits. The close relationship between sleep apnea and MetS is well established. In addition, these...

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Autores principales: Chang, Suk Won, Lee, Ha Young, Choi, Hyun Seung, Chang, Jung Hyun, Lim, Gil Chai, Kang, Ju Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562394/
https://www.ncbi.nlm.nih.gov/pubmed/37813971
http://dx.doi.org/10.1038/s41598-023-44348-4
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author Chang, Suk Won
Lee, Ha Young
Choi, Hyun Seung
Chang, Jung Hyun
Lim, Gil Chai
Kang, Ju Wan
author_facet Chang, Suk Won
Lee, Ha Young
Choi, Hyun Seung
Chang, Jung Hyun
Lim, Gil Chai
Kang, Ju Wan
author_sort Chang, Suk Won
collection PubMed
description Metabolic syndrome (MetS) is an underlying cause of various diseases and is strongly associated with mortality. In particular, it has been steadily increasing along with changes in diet and lifestyle habits. The close relationship between sleep apnea and MetS is well established. In addition, these two diseases share a common factor of obesity and have a high prevalence among obese individuals. Nevertheless, the association can vary depending on factors, such as race and sex, and research on the relatively low obesity rates among East Asians is lacking. This study aimed to investigate the association between snoring and MetS in nonobese Koreans. A total of 2478 participants (827 men and 1651 women) were enrolled in the Korean National Health and Nutrition Examination Survey from 2019 to 2020. We used the National Cholesterol Education Program Adult Treatment Panel III criteria for MetS and a snoring questionnaire. Logistic regression analysis was used to measure the association between MetS and various confounding factors according to age and sex in participants with body mass index (BMI) < 23 kg/m(2). MetS was significantly higher in participants with snoring than in those without snoring (26.9% vs. 19.6%; p = 0.007). In multivariate logistic regression analysis, age (odds ratio [OR] 1.070, 95% confidence interval [CI] 1.059–1.082, p < .001), sex (OR 1.531, 95% CI 1.139–2.058, p = 0.005), and snoring (OR 1.442, 95% CI 1.050–1.979, p = 0.024) were significantly associated with MetS in patients with a BMI < 23 kg/m(2). Finally, regression analysis showed that snoring was significantly associated with MetS in women with a BMI of less than 23 kg/m(2), especially with younger ages (40–49 years, OR 4.449, 95% CI 1.088 to 18.197, p = 0.038). Snoring was closely associated with MetS in women aged 40–50 years with a BMI of less than 23 kg/m(2) compared to other participants. However, the association was not found in women aged 60 and over. Therefore, sufficient consideration should be given to the possibility of MetS when snoring is present in nonobese middle-aged Asian women.
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spelling pubmed-105623942023-10-11 Snoring might be a warning sign for metabolic syndrome in nonobese Korean women Chang, Suk Won Lee, Ha Young Choi, Hyun Seung Chang, Jung Hyun Lim, Gil Chai Kang, Ju Wan Sci Rep Article Metabolic syndrome (MetS) is an underlying cause of various diseases and is strongly associated with mortality. In particular, it has been steadily increasing along with changes in diet and lifestyle habits. The close relationship between sleep apnea and MetS is well established. In addition, these two diseases share a common factor of obesity and have a high prevalence among obese individuals. Nevertheless, the association can vary depending on factors, such as race and sex, and research on the relatively low obesity rates among East Asians is lacking. This study aimed to investigate the association between snoring and MetS in nonobese Koreans. A total of 2478 participants (827 men and 1651 women) were enrolled in the Korean National Health and Nutrition Examination Survey from 2019 to 2020. We used the National Cholesterol Education Program Adult Treatment Panel III criteria for MetS and a snoring questionnaire. Logistic regression analysis was used to measure the association between MetS and various confounding factors according to age and sex in participants with body mass index (BMI) < 23 kg/m(2). MetS was significantly higher in participants with snoring than in those without snoring (26.9% vs. 19.6%; p = 0.007). In multivariate logistic regression analysis, age (odds ratio [OR] 1.070, 95% confidence interval [CI] 1.059–1.082, p < .001), sex (OR 1.531, 95% CI 1.139–2.058, p = 0.005), and snoring (OR 1.442, 95% CI 1.050–1.979, p = 0.024) were significantly associated with MetS in patients with a BMI < 23 kg/m(2). Finally, regression analysis showed that snoring was significantly associated with MetS in women with a BMI of less than 23 kg/m(2), especially with younger ages (40–49 years, OR 4.449, 95% CI 1.088 to 18.197, p = 0.038). Snoring was closely associated with MetS in women aged 40–50 years with a BMI of less than 23 kg/m(2) compared to other participants. However, the association was not found in women aged 60 and over. Therefore, sufficient consideration should be given to the possibility of MetS when snoring is present in nonobese middle-aged Asian women. Nature Publishing Group UK 2023-10-09 /pmc/articles/PMC10562394/ /pubmed/37813971 http://dx.doi.org/10.1038/s41598-023-44348-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Chang, Suk Won
Lee, Ha Young
Choi, Hyun Seung
Chang, Jung Hyun
Lim, Gil Chai
Kang, Ju Wan
Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title_full Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title_fullStr Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title_full_unstemmed Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title_short Snoring might be a warning sign for metabolic syndrome in nonobese Korean women
title_sort snoring might be a warning sign for metabolic syndrome in nonobese korean women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562394/
https://www.ncbi.nlm.nih.gov/pubmed/37813971
http://dx.doi.org/10.1038/s41598-023-44348-4
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