Systematic identification of gene combinations to target in innate immune cells to enhance T cell activation

Genetic engineering of immune cells has opened new avenues for improving their functionality but it remains a challenge to pinpoint which genes or combination of genes are the most beneficial to target. Here, we conduct High Multiplicity of Perturbations and Cellular Indexing of Transcriptomes and E...

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Detalles Bibliográficos
Autores principales: Xia, Lei, Komissarova, Anastasia, Jacover, Arielle, Shovman, Yehuda, Arcila-Barrera, Sebastian, Tornovsky-Babeay, Sharona, Jaya Prakashan, Milsee Mol, Nasereddin, Abdelmajeed, Plaschkes, Inbar, Nevo, Yuval, Shiff, Idit, Yosefov-Levi, Oshri, Izhiman, Tamara, Medvedev, Eleonora, Eilon, Elad, Wilensky, Asaf, Yona, Simon, Parnas, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562403/
https://www.ncbi.nlm.nih.gov/pubmed/37813864
http://dx.doi.org/10.1038/s41467-023-41792-8

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