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Deep flanking sequence engineering for efficient promoter design using DeepSEED

Designing promoters with desirable properties is essential in synthetic biology. Human experts are skilled at identifying strong explicit patterns in small samples, while deep learning models excel at detecting implicit weak patterns in large datasets. Biologists have described the sequence patterns...

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Detalles Bibliográficos
Autores principales:	Zhang, Pengcheng, Wang, Haochen, Xu, Hanwen, Wei, Lei, Liu, Liyang, Hu, Zhirui, Wang, Xiaowo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562447/ https://www.ncbi.nlm.nih.gov/pubmed/37813854 http://dx.doi.org/10.1038/s41467-023-41899-y

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