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Myocardial oxidative stress is increased in early reperfusion, but systemic antioxidative therapy does not prevent ischemia-reperfusion arrhythmias in pigs

BACKGROUND: Arrhythmias in the early phase of reperfusion after myocardial infarction (MI) are common, and can lead to hemodynamic instability or even cardiac arrest. Reactive oxygen species (ROS) are thought to play a key role in the underlying mechanisms, but evidence from large animal models is s...

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Detalles Bibliográficos
Autores principales: Haugsten Hansen, Marie, Sadredini, Mani, Hasic, Almira, Eriksen, Morten, Stokke, Mathis Korseberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562584/
https://www.ncbi.nlm.nih.gov/pubmed/37823177
http://dx.doi.org/10.3389/fcvm.2023.1223496