Cargando…

A rare case of isolated ACTH deficiency associated with a Rathke's Cleft Cyst and a review of the literature

A 78‐year‐old man was referred to clinic due to a 5‐year history of weight loss, lethargy, and pathology showing hyponatremia. In the year prior, he had a hospital admission for symptomatic hyponatremia. MRI brain during that admission showed a 1–2 mm pituitary lesion of unknown significance. Testin...

Descripción completa

Detalles Bibliográficos
Autores principales: Azam, Hamza, Tuch, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562649/
https://www.ncbi.nlm.nih.gov/pubmed/37822479
http://dx.doi.org/10.1002/ccr3.8026
Descripción
Sumario:A 78‐year‐old man was referred to clinic due to a 5‐year history of weight loss, lethargy, and pathology showing hyponatremia. In the year prior, he had a hospital admission for symptomatic hyponatremia. MRI brain during that admission showed a 1–2 mm pituitary lesion of unknown significance. Testing during this presentation revealed hypocortisolism with ACTH deficiency. Progress MRI brain revealed the presence of a Rathke's Cleft Cyst (RC). Medical management with glucocorticoids resulted in symptomatic and biochemical parameter improvement. To our knowledge this is the first reported case of isolated ACTH deficiency in the setting of a RC.