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CD98 heavy chain as a prognostic biomarker and target for cancer treatment

The SLC3A2 gene encodes for a cell-surface transmembrane protein CD98hc (4F2). CD98hc serves as a chaperone for LAT1 (SLC7A5), LAT2 (SLC7A8), y(+)LAT1 (SLC7A7), y(+)LAT2 (SLC7A6), xCT (SLC7A11) and Asc1 (SLC7A10) providing their recruitment to the plasma membrane. Together with the light subunits, i...

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Detalles Bibliográficos
Autores principales:	Xia, Pu, Dubrovska, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562705/ https://www.ncbi.nlm.nih.gov/pubmed/37823053 http://dx.doi.org/10.3389/fonc.2023.1251100

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