12/15-lipoxygenase inhibition attenuates neuroinflammation by suppressing inflammasomes

INTRODUCTION: Lipoxygenases (LOXs) have essential roles in stroke, atherosclerosis, diabetes, and hypertension. 12/15-LOX inhibition was shown to reduce infarct size and brain edema in the acute phase of experimental stroke. However, the significance of 12/15-LOX on neuroinflammation, which has an e...

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Detalles Bibliográficos
Autores principales: Cakir-Aktas, Canan, Bodur, Ebru, Yemisci, Muge, van Leyen, Klaus, Karatas, Hulya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562712/
https://www.ncbi.nlm.nih.gov/pubmed/37822799
http://dx.doi.org/10.3389/fncel.2023.1277268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562712/
https://www.ncbi.nlm.nih.gov/pubmed/37822799
http://dx.doi.org/10.3389/fncel.2023.1277268

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