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12/15-lipoxygenase inhibition attenuates neuroinflammation by suppressing inflammasomes
INTRODUCTION: Lipoxygenases (LOXs) have essential roles in stroke, atherosclerosis, diabetes, and hypertension. 12/15-LOX inhibition was shown to reduce infarct size and brain edema in the acute phase of experimental stroke. However, the significance of 12/15-LOX on neuroinflammation, which has an e...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562712/ https://www.ncbi.nlm.nih.gov/pubmed/37822799 http://dx.doi.org/10.3389/fncel.2023.1277268 |