Neuronal SAM68 differentially regulates alternative last exon splicing and ensures proper synapse development and function

Alternative splicing in the 3′UTR of mammalian genes plays a crucial role in diverse biological processes, including cell differentiation and development. SAM68 is a key splicing regulator that controls the diversity of 3′UTR isoforms through alternative last exon (ALE) selection. However, the tissu...

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Detalles Bibliográficos
Autores principales: Darwish, Mohamed, Ito, Masatoshi, Iijima, Yoko, Takase, Akinori, Ayukawa, Noriko, Suzuki, Satoko, Tanaka, Masami, Komori, Kanae, Kaida, Daisuke, Iijima, Takatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562862/
https://www.ncbi.nlm.nih.gov/pubmed/37595869
http://dx.doi.org/10.1016/j.jbc.2023.105168

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