Synthesis of new class of indole acetic acid sulfonate derivatives as ectonucleotidases inhibitors

Ectonucleotidases inhibitors (ENPPs, e5′NT (CD73) and h-TNAP) are potential therapeutic candidates for the treatment of cancer. Adenosine, the cancer-developing, and growth moiety is the resultant product of these enzymes. The synthesis of small molecules that can increase the acidic and ionizable s...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan Jadoon, Muhammad Siraj, Pelletier, Julie, Sévigny, Jean, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562900/
https://www.ncbi.nlm.nih.gov/pubmed/37822663
http://dx.doi.org/10.1039/d3ra04266a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562900/
https://www.ncbi.nlm.nih.gov/pubmed/37822663
http://dx.doi.org/10.1039/d3ra04266a

Ejemplares similares