Cargando…

Synthesis of new class of indole acetic acid sulfonate derivatives as ectonucleotidases inhibitors

Ectonucleotidases inhibitors (ENPPs, e5′NT (CD73) and h-TNAP) are potential therapeutic candidates for the treatment of cancer. Adenosine, the cancer-developing, and growth moiety is the resultant product of these enzymes. The synthesis of small molecules that can increase the acidic and ionizable s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan Jadoon, Muhammad Siraj, Pelletier, Julie, Sévigny, Jean, Iqbal, Jamshed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562900/ https://www.ncbi.nlm.nih.gov/pubmed/37822663 http://dx.doi.org/10.1039/d3ra04266a

Ejemplares similares

Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases
por: Zaigham, Zahid Hussain, et al.
Publicado: (2023)

Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors
por: Ullah, Saif, et al.
Publicado: (2022)

Generation and Characterization of Specific Antibodies to the Murine and Human Ectonucleotidase NTPDase8
por: Pelletier, Julie, et al.
Publicado: (2017)

Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 – a promising target for cancer immunotherapy
por: Schäkel, Laura, et al.
Publicado: (2022)

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39
por: Lopez, Vittoria, et al.
Publicado: (2021)

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance
por: Robson, Simon C., et al.
Publicado: (2006)

Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases
por: Afzal, Saira, et al.
Publicado: (2020)

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors
por: Schäkel, Laura, et al.
Publicado: (2020)

Synthesis of novel (E)-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors
por: Hassan, Sidra, et al.
Publicado: (2018)

Characterization and synthesis of indole-3-acetic acid in plant growth promoting Enterobacter sp.
por: Zhang, Bi-Xian, et al.
Publicado: (2021)

Palladium-catalyzed synthesis and nucleotide pyrophosphatase inhibition of benzo[4,5]furo[3,2-b]indoles
por: Do, Hoang Huy, et al.
Publicado: (2019)

Ectonucleotidases in Cancer and Inflammation
por: Stagg, John, et al.
Publicado: (2012)

NTPDase1/CD39 Ectonucleotidase Is Necessary for Normal Arterial Diameter Adaptation to Flow
por: Favre, Julie, et al.
Publicado: (2023)

Design, Synthesis, and Biological Evaluation of Novel Dihydropyridine and Pyridine Analogs as Potent Human Tissue Nonspecific Alkaline Phosphatase Inhibitors with Anticancer Activity: ROS and DNA Damage-Induced Apoptosis
por: Khan, Nazeer Ahmad, et al.
Publicado: (2022)

Ectonucleotidases in Intestinal and Hepatic Inflammation
por: Vuerich, Marta, et al.
Publicado: (2019)

Ectonucleotidases in Acute and Chronic Inflammation
por: Giuliani, Anna Lisa, et al.
Publicado: (2021)

Facile one-pot synthesis of sulfonyl fluorides from sulfonates or sulfonic acids
por: Jiang, Ying, et al.
Publicado: (2019)

Naturally based ionic liquids with indole-3-acetate anions and cations derived from cinchona alkaloids
por: Rzemieniecki, Tomasz, et al.
Publicado: (2021)

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
por: Heravi, Majid M., et al.
Publicado: (2021)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors
por: Deng, Xiaobing, et al.
Publicado: (2018)

A multicomponent tetrazolo indole synthesis
por: Lei, Xiaofang, et al.
Publicado: (2021)

Silyloxymethanesulfinate as a sulfoxylate equivalent for the modular synthesis of sulfones and sulfonyl derivatives
por: Kim, Dae-Kwon, et al.
Publicado: (2020)

Design, synthesis, and herbicidal activity of indole-3-carboxylic acid derivatives as potential transport inhibitor response 1 antagonists
por: Wang, Xing, et al.
Publicado: (2022)

A novel class of C14-sulfonate-tetrandrine derivatives as potential chemotherapeutic agents for hepatocellular carcinoma
por: Jiang, Taibai, et al.
Publicado: (2023)

Appraisal of novel azomethine–thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors: synthesis and molecular docking studies
por: Channar, Pervaiz Ali, et al.
Publicado: (2022)

Folic acid-sulfonamide conjugates as antibacterial agents: design, synthesis and molecular docking studies
por: Shahzad, Shabnam, et al.
Publicado: (2020)

Facile synthesis of sulfonyl fluorides from sulfonic acids
por: Thomson, Brodie J., et al.
Publicado: (2022)

Visible-light-induced one-pot synthesis of sulfonic esters via multicomponent reaction of arylazo sulfones and alcohols
por: Luu, Truong Giang, et al.
Publicado: (2022)

A multifunctional ratiometric electrochemical sensor for combined determination of indole-3-acetic acid and salicylic acid
por: Hu, Ye, et al.
Publicado: (2020)

Impaired Expression of Ectonucleotidases in Ectopic and Eutopic Endometrial Tissue Is in Favor of ATP Accumulation in the Tissue Microenvironment in Endometriosis
por: Trapero, Carla, et al.
Publicado: (2019)

Synthesis, characterization, and in vitro anti-cholinesterase screening of novel indole amines
por: Gondal, Humaira Yasmeen, et al.
Publicado: (2023)

Nitroketene N,S-acetals: synergistic building blocks for the synthesis of heterocycles
por: Saigal,, et al.
Publicado: (2019)

Synthesis and antitumor effects of novel benzyl naphthyl sulfoxide/sulfone derivatives derived from Rigosertib
por: Tang, Lin, et al.
Publicado: (2021)

Expression and Distribution of Ectonucleotidases in Mouse Urinary Bladder
por: Yu, Weiqun, et al.
Publicado: (2011)

Ectonucleotidase Modulation of Lymphocyte Function in Gut and Liver
por: Savio, Luiz Eduardo Baggio, et al.
Publicado: (2021)

Synthesis and Bioactivity of Novel Sulfonate Scaffold-Containing Pyrazolecarbamide Derivatives as Antifungal and Antiviral Agents
por: Lei, Zhi-Wei, et al.
Publicado: (2022)

Synthesis and photophysical characterization of fluorescent indole nucleoside analogues
por: Sawyer, Jacob M., et al.
Publicado: (2023)

Synthesis and characterization of a novel crosslinkable side-chain sulfonated poly(arylene ether sulfone) copolymer proton exchange membranes
por: Wang, Shouping, et al.
Publicado: (2020)

Introducing a sulfone-embedded anhydride to the anhydride-imine reaction for the modular synthesis of N-heterocyclic sulfones bearing vicinal stereocenters
por: Beng, Timothy K., et al.
Publicado: (2023)

Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions
por: Miao, Weihang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gd8hkc4vk4p3l5cg54cganad4t