Cargando…

Glycosylated Delta-receptor-binding domain mucosal vaccine elicits broadly neutralizing antibodies with protection against SARS-CoV-2 challenge

Mucosal COVID-19 vaccines are needed to block SARS-CoV-2 infection at the mucosal site. Intranasal delivery of a glycosylated Delta variant receptor-binding domain (Delta-RBD) mucosal vaccine elicited potent and balanced systemic antibody titers comparable to those induced by the intramuscular injec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Xiaoqing, Verma, Abhishek K., Wang, Gang, Shi, Juan, Perlman, Stanley, Du, Lanying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563057/ https://www.ncbi.nlm.nih.gov/pubmed/37822493 http://dx.doi.org/10.1016/j.isci.2023.108033

Ejemplares similares

mRNA vaccines elicit potent neutralization against multiple SARS-CoV-2 omicron subvariants and other variants of concern
por: Wang, Gang, et al.
Publicado: (2022)

MERS-CoV RBD-mRNA vaccine induces potent and broadly neutralizing antibodies with protection against MERS-CoV infection
por: Tai, Wanbo, et al.
Publicado: (2023)

A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 Infection
por: Shi, Juan, et al.
Publicado: (2022)

Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses
por: Walls, Alexandra C., et al.
Publicado: (2021)

Broad and potent neutralizing antibodies are elicited in vaccinated individuals following Delta/BA.1 breakthrough infection
por: Seow, Jeffrey, et al.
Publicado: (2023)

Designer antigens for elicitation of broadly neutralizing antibodies against HIV
por: Kok, Tuckweng, et al.
Publicado: (2014)

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
por: Sok, Devin, et al.
Publicado: (2017)

Development of an anti-HIV vaccine eliciting broadly neutralizing antibodies
por: Ahmed, Yousuf, et al.
Publicado: (2017)

RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge
por: Shi, Juan, et al.
Publicado: (2022)

Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies
por: Chuang, Gwo-Yu, et al.
Publicado: (2020)

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
por: Walls, Alexandra C., et al.
Publicado: (2021)

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
por: Walls, Alexandra C., et al.
Publicado: (2021)

Eliciting neutralizing antibodies with gp120 outer domain
por: Qin, Y, et al.
Publicado: (2012)

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
por: McCoy, Laura E., et al.
Publicado: (2012)

Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
por: Huang, Deli, et al.
Publicado: (2020)

Multiscale affinity maturation simulations to elicit broadly neutralizing antibodies against HIV
por: Conti, Simone, et al.
Publicado: (2022)

Development of Receptor Binding Domain (RBD)‐Conjugated Nanoparticle Vaccines with Broad Neutralization against SARS‐CoV‐2 Delta and Other Variants
por: Chen, Ran, et al.
Publicado: (2022)

Effective vaccination strategy using SARS-CoV-2 spike cocktail against Omicron and other variants of concern
por: Shi, Juan, et al.
Publicado: (2022)

Eliciting broadly neutralizing antibodies against HIV-1 that target gp41 MPER
por: Han, D, et al.
Publicado: (2012)

Fc-Based Recombinant Henipavirus Vaccines Elicit Broad Neutralizing Antibody Responses in Mice
por: Li, Yaohui, et al.
Publicado: (2020)

HIV Coinfection Provides Insights for the Design of Vaccine Cocktails to Elicit Broadly Neutralizing Antibodies
por: Sheward, Daniel J., et al.
Publicado: (2022)

SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies
por: Yang, Yang, et al.
Publicado: (2021)

Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA
por: Portnoff, Alyse D., et al.
Publicado: (2020)

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity
por: Du, Lanying, et al.
Publicado: (2009)

Retraction: eliciting broadly neutralizing antibodies against HIV-1 that target gp41 MPER
por: Han, D, et al.
Publicado: (2014)

Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
por: Huang, Deli, et al.
Publicado: (2020)

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques
por: Nelson, Ashley N., et al.
Publicado: (2023)

Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines
por: Du, Lanying, et al.
Publicado: (2006)

Non-glycosylated SARS-CoV-2 RBD elicited a robust neutralizing antibody response in mice
por: Ke, Qian, et al.
Publicado: (2022)

SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
por: Walls, Alexandra C., et al.
Publicado: (2022)

Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2
por: Luo, Mengxiao, et al.
Publicado: (2023)

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
por: Sok, Devin, et al.
Publicado: (2013)

Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by N-glycosylation
por: Harmsen, M. M., et al.
Publicado: (2009)

Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies
por: Cheeseman, Hannah M., et al.
Publicado: (2016)

Heterologous SARS-CoV-2 spike protein booster elicits durable and broad antibody responses against the receptor-binding domain
por: Takano, Tomohiro, et al.
Publicado: (2023)

Broad reception for coronavirus
por: Gallagher, Tom, et al.
Publicado: (2013)

Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody
por: Liu, Jinny L., et al.
Publicado: (2021)

Omicron infection elicits a broad neutralizing response in hospitalized patients with COVID-19
por: McNally, Elizabeth M.
Publicado: (2022)

Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants
por: Liu, Yubin, et al.
Publicado: (2023)

Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination
por: Ju, Bin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_trrn86dmauf4ib37r9p1qmkspt