Cargando…

Specific Targeting of STAT3 in B Cells Suppresses Progression of B Cell Lymphoma

The signal transducer and activator of transcription 3 (STAT3), which regulates multiple oncogenic processes, has been found to be constitutively activated in lymphoma, suggesting its potential as a therapeutic target. Here, we constructed an anti-CD19-N-(4-carboxycyclohexylmethyl) maleimide N-hydro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Lipei, Zhou, Mingqian, Kong, Xiangyu, Wu, Shouzhen, Ding, Chuanlin, Hu, Xiaoling, Guo, Haixun, Yan, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563066/ https://www.ncbi.nlm.nih.gov/pubmed/37686472 http://dx.doi.org/10.3390/ijms241713666

Ejemplares similares

Liver-specific knockout of B cell lymphoma 6 suppresses progression of non-alcoholic steatohepatitis in mice
por: Chikada, Hiromi, et al.
Publicado: (2020)

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas
por: Pinkney, Kerice A., et al.
Publicado: (2015)

STAT3 Targets Suggest Mechanisms of Aggressive Tumorigenesis in Diffuse Large B-Cell Lymphoma
por: Hardee, Jennifer, et al.
Publicado: (2013)

B Cell Lymphoma Immunotherapy Using TLR9-Targeted Oligonucleotide STAT3 Inhibitors
por: Zhao, Xingli, et al.
Publicado: (2018)

The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression
por: Geller, Anne E., et al.
Publicado: (2022)

Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation
por: Yao, Su, et al.
Publicado: (2017)

Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8(+) Thymocytes
por: Chen, Bo, et al.
Publicado: (2013)

Inhibition of the STAT3 target SGK1 sensitizes diffuse large B cell lymphoma cells to AKT inhibitors
por: Lu, Li, et al.
Publicado: (2019)

STAT-3 RNAscope Determination in Human Diffuse Large B-Cell Lymphoma()
por: Tamma, Roberto, et al.
Publicado: (2019)

Immune targeted therapy for diffuse large B cell lymphoma
por: Zheng, Yaxin, et al.
Publicado: (2021)

Identification of STAT5A and STAT5B Target Genes in Human T Cells
por: Kanai, Takahiro, et al.
Publicado: (2014)

STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas
por: Pan, Yi-Ru, et al.
Publicado: (2018)

Progression and Transformation of Clonally Heterogeneous B-cell Lymphoma
por: Weiss, Robert F., et al.
Publicado: (2015)

Rapidly Progressing Pituitary Mass in B-cell Lymphoma
por: Morita, Shuhei, et al.
Publicado: (2019)

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases
por: Miletic, Ana V., et al.
Publicado: (2010)

Targeting primary mediastinal B-cell lymphoma
por: Wagner, Simon D.
Publicado: (2014)

CD81 as target for B cell lymphomas
por: Küppers, Ralf
Publicado: (2019)

Genetic polymorphisms of STAT3 correlated with prognosis in diffuse large B-cell lymphoma patients treated with rituximab
por: Hu, Yunfei, et al.
Publicado: (2014)

P1217: TARGETING HSP110 IN COMBINATION WITH SELINEXOR IN PRIMARY MEDIASTINAL B-CELL LYMPHOMA AND IN CLASSICAL HODGKIN LYMPHOMA INHIBITS STAT6 ACTIVATION AND IMPAIRS LYMPHOMA CELL GROWTH
por: Durand, Manon, et al.
Publicado: (2023)

Tuberatolide B Suppresses Cancer Progression by Promoting ROS-Mediated Inhibition of STAT3 Signaling
por: Choi, Youn Kyung, et al.
Publicado: (2017)

EBV Latent Membrane Protein 1 Activates Akt, NFκB, and Stat3 in B Cell Lymphomas
por: Shair, Kathy H. Y, et al.
Publicado: (2007)

B Cells Promote Tumor Progression via STAT3 Regulated-Angiogenesis
por: Yang, Chunmei, et al.
Publicado: (2013)

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL)
por: Ritz, Olga, et al.
Publicado: (2013)

STAT3 Expression and Activity are Up‐Regulated in Diffuse Large B Cell Lymphoma of Dogs
por: Assumpção, A.L.F.V., et al.
Publicado: (2017)

STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer
por: Li, Rui, et al.
Publicado: (2017)

Chimeric antigen receptor T cells to target CD79b in B-cell lymphomas
por: Chu, Fuliang, et al.
Publicado: (2023)

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
por: Brault, L, et al.
Publicado: (2012)

ATMIN Is Required for Maintenance of Genomic Stability and Suppression of B Cell Lymphoma
por: Loizou, Joanna I., et al.
Publicado: (2011)

A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture
por: Zheng, M, et al.
Publicado: (2016)

Ratios of Four STAT3 Splice Variants in Human Eosinophils and Diffuse Large B Cell Lymphoma Cells
por: Turton, Keren B., et al.
Publicado: (2015)

Targeting the Bcl-2 Family in B Cell Lymphoma
por: Adams, Clare M., et al.
Publicado: (2019)

Targeting N-myristoylation for therapy of B-cell lymphomas
por: Beauchamp, Erwan, et al.
Publicado: (2020)

Epigenetic targets in B- and T-cell lymphomas: latest developments
por: Ribeiro, Marcelo Lima, et al.
Publicado: (2023)

Lymphoplasmacytic lymphoma associated with diffuse large B-cell lymphoma: Progression or divergent evolution?
por: Boiza-Sánchez, Macarena, et al.
Publicado: (2020)

THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
por: Cayrol, Florencia, et al.
Publicado: (2017)

STAT3 deficiency in B cells exacerbates uveitis by promoting expansion of pathogenic lymphocytes and suppressing regulatory B cells (Bregs) and Tregs
por: Oladipupo, Favour O., et al.
Publicado: (2020)

Characterization of STAT6 Target Genes in Human B Cells and Lung Epithelial Cells
por: Kanai, Akinori, et al.
Publicado: (2011)

Patient-Specific Modeling of Diffuse Large B-Cell Lymphoma
por: Thobe, Kirsten, et al.
Publicado: (2021)

A Novel VHH Antibody Targeting the B Cell-Activating Factor for B-Cell Lymphoma
por: Wu, Wen, et al.
Publicado: (2014)

High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma
por: ZL, Wu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_2cuq7nvhf2b2nq2h4g6c1vt39q