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The small HDL particle hypothesis of Alzheimer’s disease
We propose the hypothesis that small high-density lipoprotein (HDL) particles reduce the risk of Alzheimer’s disease (AD) by virtue of their capacity to exchange lipids, affecting neuronal membrane composition and vascular and synaptic functions. Concentrations of small HDLs in cerebrospinal fluid (...
Autores principales: | Martinez, Ashley E., Weissberger, Gali, Kuklenyik, Zsuzsanna, He, Xulei, Meuret, Cristiana, Parekh, Trusha, Rees, Jon C., Parks, Bryan A., Gardner, Michael S., King, Sarah M., Collier, Timothy S., Harrington, Michael G., Sweeney, Melanie D., Wang, Xinhui, Zlokovic, Berislav V., Joe, Elizabeth, Nation, Daniel A., Schneider, Lon S., Chui, Helena C., Barr, John R., Han, S. Duke, Krauss, Ronald M., Yassine, Hussein N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563117/ https://www.ncbi.nlm.nih.gov/pubmed/35416404 http://dx.doi.org/10.1002/alz.12649 |
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