Augmenting Granzyme B–Expressing NK Cells by Invariant NKT Ligand–Loaded APCs in Patients with Postoperative Early Stage Non–Small Cell Lung Cancer: Results of a Randomized Phase II Study

NK cells are major effector cells involved in the elimination of early tumors and prevent metastasis. They often have an impaired function in patients with cancer. Preclinical studies have demonstrated NK cell activation as the adjunctive effect of invariant NKT (iNKT) cells. Activation of iNKT cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Iyoda, Tomonori, Shimizu, Kanako, Kawamura, Masami, Shinga, Jun, Watanabe, Takashi, Fukunaga, Koya, Mushiroda, Taisei, Saka, Hideo, Kitagawa, Chiyoe, Shimamatsu, Shin-ichiro, Takenoyama, Mitsuhiro, Suehiro, Youko, Imai, Takumi, Shintani, Ayumi, Ito, Suminobu, Fujii, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563390/
https://www.ncbi.nlm.nih.gov/pubmed/36637516
http://dx.doi.org/10.4049/immunohorizons.2200091

Ejemplares similares

Ejemplares similares