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Extracellular microRNA 130b‐3p inhibits eCIRP‐induced inflammation

Although microRNAs regulate mRNA expression intracellularly, they are often released into the circulation in inflammatory diseases. During sepsis, secreted extracellular cold‐inducible RNA‐binding protein (eCIRP) acts as a damage‐associated molecular pattern (DAMP), inducing tissue damage by elevati...

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Detalles Bibliográficos
Autores principales: Gurien, Steven D, Aziz, Monowar, Jin, Hui, Wang, Haichao, He, Mingzhu, Al‐Abed, Yousef, Nicastro, Jeffrey M, Coppa, Gene F, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563445/
https://www.ncbi.nlm.nih.gov/pubmed/31724825
http://dx.doi.org/10.15252/embr.201948075

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