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STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563567/ https://www.ncbi.nlm.nih.gov/pubmed/37822820 http://dx.doi.org/10.6026/97320630019499 |
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author | Selladurai, Karthickraj Selvaganesh, Sahana Veeraraghavan, Vishnu Priya Nesappan, Thiyaneswaran Eswaramoorthy, Rajalakshmanan |
author_facet | Selladurai, Karthickraj Selvaganesh, Sahana Veeraraghavan, Vishnu Priya Nesappan, Thiyaneswaran Eswaramoorthy, Rajalakshmanan |
author_sort | Selladurai, Karthickraj |
collection | PubMed |
description | Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter actinomycetemcomitans (D7S-1), Centipeda periodontii, Campylobacter gracilisi, Fusobacterium nucleatumi, Slackia exigua, Prevotella intermedia, Tannerella forsythia, Staphylococcus aureus, Bacteroides fragilis, and Bacteroides fragilis. Hence, a user-defined query was used to conduct analysis on the provided bacterial strains whose molecular data available in the STITCH database. Thus, we used the STITCH tool to examine protein interactions and the VirulentPred tool to assess pathogenicity using the known molecular data on glycrhizzin and peri implant pathogens. Data shows that glycyrrhizin interacts with peri implant pathogens. |
format | Online Article Text |
id | pubmed-10563567 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-105635672023-10-11 STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota Selladurai, Karthickraj Selvaganesh, Sahana Veeraraghavan, Vishnu Priya Nesappan, Thiyaneswaran Eswaramoorthy, Rajalakshmanan Bioinformation Research Article Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter actinomycetemcomitans (D7S-1), Centipeda periodontii, Campylobacter gracilisi, Fusobacterium nucleatumi, Slackia exigua, Prevotella intermedia, Tannerella forsythia, Staphylococcus aureus, Bacteroides fragilis, and Bacteroides fragilis. Hence, a user-defined query was used to conduct analysis on the provided bacterial strains whose molecular data available in the STITCH database. Thus, we used the STITCH tool to examine protein interactions and the VirulentPred tool to assess pathogenicity using the known molecular data on glycrhizzin and peri implant pathogens. Data shows that glycyrrhizin interacts with peri implant pathogens. Biomedical Informatics 2023-04-30 /pmc/articles/PMC10563567/ /pubmed/37822820 http://dx.doi.org/10.6026/97320630019499 Text en © 2023 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |
spellingShingle | Research Article Selladurai, Karthickraj Selvaganesh, Sahana Veeraraghavan, Vishnu Priya Nesappan, Thiyaneswaran Eswaramoorthy, Rajalakshmanan STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title | STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title_full | STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title_fullStr | STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title_full_unstemmed | STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title_short | STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota |
title_sort | stitch enabled molecular interaction of glycrhizzin with peri-implant microbiota |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563567/ https://www.ncbi.nlm.nih.gov/pubmed/37822820 http://dx.doi.org/10.6026/97320630019499 |
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