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STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota

Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter...

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Autores principales: Selladurai, Karthickraj, Selvaganesh, Sahana, Veeraraghavan, Vishnu Priya, Nesappan, Thiyaneswaran, Eswaramoorthy, Rajalakshmanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563567/
https://www.ncbi.nlm.nih.gov/pubmed/37822820
http://dx.doi.org/10.6026/97320630019499
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author Selladurai, Karthickraj
Selvaganesh, Sahana
Veeraraghavan, Vishnu Priya
Nesappan, Thiyaneswaran
Eswaramoorthy, Rajalakshmanan
author_facet Selladurai, Karthickraj
Selvaganesh, Sahana
Veeraraghavan, Vishnu Priya
Nesappan, Thiyaneswaran
Eswaramoorthy, Rajalakshmanan
author_sort Selladurai, Karthickraj
collection PubMed
description Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter actinomycetemcomitans (D7S-1), Centipeda periodontii, Campylobacter gracilisi, Fusobacterium nucleatumi, Slackia exigua, Prevotella intermedia, Tannerella forsythia, Staphylococcus aureus, Bacteroides fragilis, and Bacteroides fragilis. Hence, a user-defined query was used to conduct analysis on the provided bacterial strains whose molecular data available in the STITCH database. Thus, we used the STITCH tool to examine protein interactions and the VirulentPred tool to assess pathogenicity using the known molecular data on glycrhizzin and peri implant pathogens. Data shows that glycyrrhizin interacts with peri implant pathogens.
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spelling pubmed-105635672023-10-11 STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota Selladurai, Karthickraj Selvaganesh, Sahana Veeraraghavan, Vishnu Priya Nesappan, Thiyaneswaran Eswaramoorthy, Rajalakshmanan Bioinformation Research Article Glycyrrhizin is present in the root extract of the licorice plant used for various conditions, including gastric ulcers. Therefore, it is of interest to document the STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota. The peri implant pathogens includes Aggregatibacter actinomycetemcomitans (D7S-1), Centipeda periodontii, Campylobacter gracilisi, Fusobacterium nucleatumi, Slackia exigua, Prevotella intermedia, Tannerella forsythia, Staphylococcus aureus, Bacteroides fragilis, and Bacteroides fragilis. Hence, a user-defined query was used to conduct analysis on the provided bacterial strains whose molecular data available in the STITCH database. Thus, we used the STITCH tool to examine protein interactions and the VirulentPred tool to assess pathogenicity using the known molecular data on glycrhizzin and peri implant pathogens. Data shows that glycyrrhizin interacts with peri implant pathogens. Biomedical Informatics 2023-04-30 /pmc/articles/PMC10563567/ /pubmed/37822820 http://dx.doi.org/10.6026/97320630019499 Text en © 2023 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Selladurai, Karthickraj
Selvaganesh, Sahana
Veeraraghavan, Vishnu Priya
Nesappan, Thiyaneswaran
Eswaramoorthy, Rajalakshmanan
STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title_full STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title_fullStr STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title_full_unstemmed STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title_short STITCH enabled molecular interaction of glycrhizzin with peri-implant microbiota
title_sort stitch enabled molecular interaction of glycrhizzin with peri-implant microbiota
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563567/
https://www.ncbi.nlm.nih.gov/pubmed/37822820
http://dx.doi.org/10.6026/97320630019499
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