Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC

Wnt signaling pathway plays a critical role in tumor progression and metastasis of various cancer types. Therefore, it is of interest to document the molecular docking analysis of proflavin with the Wnt pathway targets (GSK3β, β-catenin, and VIM) for oral squamous cell carcinoma (OSCC). These result...

Descripción completa

Detalles Bibliográficos
Autores principales: Pazhani, Jayanthi, Veeraraghavan, Vishnu Priya, Jayaraman, Selvaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563574/
https://www.ncbi.nlm.nih.gov/pubmed/37822816
http://dx.doi.org/10.6026/97320630019464
_version_ 1785118361848381440
author Pazhani, Jayanthi
Veeraraghavan, Vishnu Priya
Jayaraman, Selvaraj
author_facet Pazhani, Jayanthi
Veeraraghavan, Vishnu Priya
Jayaraman, Selvaraj
author_sort Pazhani, Jayanthi
collection PubMed
description Wnt signaling pathway plays a critical role in tumor progression and metastasis of various cancer types. Therefore, it is of interest to document the molecular docking analysis of proflavin with the Wnt pathway targets (GSK3β, β-catenin, and VIM) for oral squamous cell carcinoma (OSCC). These results suggest that targeting the wnt signaling downstream targets with proflavine might leads to the better outcome for therapeutic outcome for the inhibition of invasion and metastasis in oral squamous cell carcinoma.
format Online
Article
Text
id pubmed-10563574
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Biomedical Informatics
record_format MEDLINE/PubMed
spelling pubmed-105635742023-10-11 Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC Pazhani, Jayanthi Veeraraghavan, Vishnu Priya Jayaraman, Selvaraj Bioinformation Research Article Wnt signaling pathway plays a critical role in tumor progression and metastasis of various cancer types. Therefore, it is of interest to document the molecular docking analysis of proflavin with the Wnt pathway targets (GSK3β, β-catenin, and VIM) for oral squamous cell carcinoma (OSCC). These results suggest that targeting the wnt signaling downstream targets with proflavine might leads to the better outcome for therapeutic outcome for the inhibition of invasion and metastasis in oral squamous cell carcinoma. Biomedical Informatics 2023-04-30 /pmc/articles/PMC10563574/ /pubmed/37822816 http://dx.doi.org/10.6026/97320630019464 Text en © 2023 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Pazhani, Jayanthi
Veeraraghavan, Vishnu Priya
Jayaraman, Selvaraj
Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title_full Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title_fullStr Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title_full_unstemmed Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title_short Molecular docking analysis of proflavin with the Wnt pathway targets for OSCC
title_sort molecular docking analysis of proflavin with the wnt pathway targets for oscc
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563574/
https://www.ncbi.nlm.nih.gov/pubmed/37822816
http://dx.doi.org/10.6026/97320630019464
work_keys_str_mv AT pazhanijayanthi moleculardockinganalysisofproflavinwiththewntpathwaytargetsforoscc
AT veeraraghavanvishnupriya moleculardockinganalysisofproflavinwiththewntpathwaytargetsforoscc
AT jayaramanselvaraj moleculardockinganalysisofproflavinwiththewntpathwaytargetsforoscc

Ejemplares similares