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Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh

Influenza virological surveillance was conducted in Bangladesh from January to December 2021 in live poultry markets (LPMs) and in Tanguar Haor, a wetland region where domestic ducks have frequent contact with migratory birds. The predominant viruses circulating in LPMs were low pathogenic avian inf...

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Autores principales: Barman, Subrata, Turner, Jasmine C. M., Kamrul Hasan, M., Akhtar, Sharmin, Jeevan, Trushar, Franks, John, Walker, David, Mukherjee, Nabanita, Seiler, Patrick, Kercher, Lisa, McKenzie, Pamela, Webster, Robert G., Feeroz, Mohammed M., Webby, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563617/
https://www.ncbi.nlm.nih.gov/pubmed/37622753
http://dx.doi.org/10.1080/22221751.2023.2252510
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author Barman, Subrata
Turner, Jasmine C. M.
Kamrul Hasan, M.
Akhtar, Sharmin
Jeevan, Trushar
Franks, John
Walker, David
Mukherjee, Nabanita
Seiler, Patrick
Kercher, Lisa
McKenzie, Pamela
Webster, Robert G.
Feeroz, Mohammed M.
Webby, Richard J.
author_facet Barman, Subrata
Turner, Jasmine C. M.
Kamrul Hasan, M.
Akhtar, Sharmin
Jeevan, Trushar
Franks, John
Walker, David
Mukherjee, Nabanita
Seiler, Patrick
Kercher, Lisa
McKenzie, Pamela
Webster, Robert G.
Feeroz, Mohammed M.
Webby, Richard J.
author_sort Barman, Subrata
collection PubMed
description Influenza virological surveillance was conducted in Bangladesh from January to December 2021 in live poultry markets (LPMs) and in Tanguar Haor, a wetland region where domestic ducks have frequent contact with migratory birds. The predominant viruses circulating in LPMs were low pathogenic avian influenza (LPAI) H9N2 and clade 2.3.2.1a highly pathogenic avian influenza (HPAI) H5N1 viruses. Additional LPAIs were found in both LPM (H4N6) and Tanguar Haor wetlands (H7N7). Genetic analyses of these LPAIs strongly suggested long-distance movement of viruses along the Central Asian migratory bird flyway. We also detected a novel clade 2.3.4.4b H5N1 virus from ducks in free-range farms in Tanguar Haor that was similar to viruses first detected in October 2020 in The Netherlands but with a different PB2. Identification of clade 2.3.4.4b HPAI H5N1 viruses in Tanguar Haor provides continued support of the role of migratory birds in transboundary movement of influenza A viruses (IAV), including HPAI viruses. Domestic ducks in free range farm in wetland areas, like Tangua Haor, serve as a conduit for the introduction of LPAI and HPAI viruses into Bangladesh. Clade 2.3.4.4b viruses have dominated in many regions of the world since mid-2021, and it remains to be seen if these viruses will replace the endemic clade 2.3.2.1a H5N1 viruses in Bangladesh.
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spelling pubmed-105636172023-10-11 Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh Barman, Subrata Turner, Jasmine C. M. Kamrul Hasan, M. Akhtar, Sharmin Jeevan, Trushar Franks, John Walker, David Mukherjee, Nabanita Seiler, Patrick Kercher, Lisa McKenzie, Pamela Webster, Robert G. Feeroz, Mohammed M. Webby, Richard J. Emerg Microbes Infect Research Article Influenza virological surveillance was conducted in Bangladesh from January to December 2021 in live poultry markets (LPMs) and in Tanguar Haor, a wetland region where domestic ducks have frequent contact with migratory birds. The predominant viruses circulating in LPMs were low pathogenic avian influenza (LPAI) H9N2 and clade 2.3.2.1a highly pathogenic avian influenza (HPAI) H5N1 viruses. Additional LPAIs were found in both LPM (H4N6) and Tanguar Haor wetlands (H7N7). Genetic analyses of these LPAIs strongly suggested long-distance movement of viruses along the Central Asian migratory bird flyway. We also detected a novel clade 2.3.4.4b H5N1 virus from ducks in free-range farms in Tanguar Haor that was similar to viruses first detected in October 2020 in The Netherlands but with a different PB2. Identification of clade 2.3.4.4b HPAI H5N1 viruses in Tanguar Haor provides continued support of the role of migratory birds in transboundary movement of influenza A viruses (IAV), including HPAI viruses. Domestic ducks in free range farm in wetland areas, like Tangua Haor, serve as a conduit for the introduction of LPAI and HPAI viruses into Bangladesh. Clade 2.3.4.4b viruses have dominated in many regions of the world since mid-2021, and it remains to be seen if these viruses will replace the endemic clade 2.3.2.1a H5N1 viruses in Bangladesh. Taylor & Francis 2023-08-25 /pmc/articles/PMC10563617/ /pubmed/37622753 http://dx.doi.org/10.1080/22221751.2023.2252510 Text en © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
spellingShingle Research Article
Barman, Subrata
Turner, Jasmine C. M.
Kamrul Hasan, M.
Akhtar, Sharmin
Jeevan, Trushar
Franks, John
Walker, David
Mukherjee, Nabanita
Seiler, Patrick
Kercher, Lisa
McKenzie, Pamela
Webster, Robert G.
Feeroz, Mohammed M.
Webby, Richard J.
Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title_full Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title_fullStr Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title_full_unstemmed Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title_short Emergence of a new genotype of clade 2.3.4.4b H5N1 highly pathogenic avian influenza A viruses in Bangladesh
title_sort emergence of a new genotype of clade 2.3.4.4b h5n1 highly pathogenic avian influenza a viruses in bangladesh
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563617/
https://www.ncbi.nlm.nih.gov/pubmed/37622753
http://dx.doi.org/10.1080/22221751.2023.2252510
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