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Relationship of body mass index and visceral fat area combination with arterial stiffness and cardiovascular risk in cardiovascular disease-free people: NHANES (2011–2018)

BACKGROUND: Obesity and arterial stiffness are strongly associated with cardiovascular disease; however, their relationship remains controversial. METHODS: Body mass index was measured using anthropometric evaluation, and visceral fat area was calculated using an absorptiometry scan. RESULTS: The da...

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Detalles Bibliográficos
Autores principales: Huang, Yuan, Hu, Yunyun, Bao, Bingshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563637/
https://www.ncbi.nlm.nih.gov/pubmed/37668220
http://dx.doi.org/10.1530/EC-23-0291
Descripción
Sumario:BACKGROUND: Obesity and arterial stiffness are strongly associated with cardiovascular disease; however, their relationship remains controversial. METHODS: Body mass index was measured using anthropometric evaluation, and visceral fat area was calculated using an absorptiometry scan. RESULTS: The data of 5309 participants were collected from NHANES (National Health and Nutrition Examination Survey) (2011–2018). Based on the normal-weight normal visceral fat group that was considered as a reference, ePWV increased in all other groups, with the obese grade 2 visceral obesity group increasing the most by 26.35 cm/s (95% CI: 13.52, 39.18, P < 0.001), followed by normal-weight visceral obesity group 24.43 cm/s (95% CI: 1.88, 46.98, P = 0.035), which was even higher than obese grade 1 visceral obesity (β: 21.16, 95% CI: 9.24, 33.07, P = 0.001), obese grade 2 normal visceral fat group (β: 13.8; 95% CI: 0.10, 27.5, P = 0.048) and overweight visceral obesity group (β: 10.23; 95% CI: 1.89, 18.57, P = 0.018). For the 10-year cardiovascular risk, the obese grade 2 visceral obesity group had a 9.56-fold increase in compared with the control (OR: 10.56, 95% CI: 4.06, 27.51, P < 0.0001). Normal-weight visceral obesity, obese grade 1 visceral obesity, and overweight visceral obesity groups increased by 8.03-fold (OR: 9.03, 95% CI: 2.66, 30.69; P < 0.001), 7.91-fold (OR: 8.91, 95% CI: 3.82, 20.79, P < 0.001), and 7.28-fold (OR: 8.28, 95% CI: 3.19, 21.46, P < 0.001). The risk was lower in the normal visceral fat group. Except for the obese grade 2 normal visceral fat group, there was no significant difference in other groups. CONCLUSIONS: Normal-weight visceral obesity was associated with higher arterial stiffness and 10-year cardiovascular risk.