Cargando…

Effects of adipocyte-specific Dkk1 deletion on bone homeostasis and obesity-induced bone loss in male mice

The link between obesity and low bone strength has become a significant medical concern. The canonical Wnt signaling pathway is a key regulator of mesenchymal stem cell differentiation into either osteoblasts or adipocytes with active Wnt signaling promoting osteoblastogenesis. Our previous research...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daamouch, Souad, Thiele, Sylvia, Hofbauer, Lorenz, Rauner, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563648/ https://www.ncbi.nlm.nih.gov/pubmed/37615386 http://dx.doi.org/10.1530/EC-23-0251

Ejemplares similares

Loss of Dkk-1 in Osteocytes Mitigates Alveolar Bone Loss in Mice With Periodontitis
por: Goes, Paula, et al.
Publicado: (2019)

MicroRNA and Diabetic Bone Disease
por: Daamouch, Souad, et al.
Publicado: (2022)

Mice lacking DKK1 in T cells exhibit high bone mass and are protected from estrogen-deficiency-induced bone loss
por: Lehmann, Juliane, et al.
Publicado: (2021)

Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss
por: Rauner, Martina, et al.
Publicado: (2021)

Contributions of Dickkopf‐1 to Obesity‐Induced Bone Loss and Marrow Adiposity
por: Colditz, Juliane, et al.
Publicado: (2020)

Low Bone Turnover Due to Hypothyroidism or Anti-Resorptive Treatment Does Not Affect Whole-Body Glucose Homeostasis in Male Mice
por: Lademann, Franziska, et al.
Publicado: (2022)

Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus
por: Hildebrandt, Nick, et al.
Publicado: (2021)

Luspatercept mitigates bone loss driven by myelodysplastic neoplasms and estrogen-deficiency in mice
por: Weidner, Heike, et al.
Publicado: (2022)

Thy-1 Deficiency Augments Bone Loss in Obesity by Affecting Bone Formation and Resorption
por: Picke, Ann-Kristin, et al.
Publicado: (2018)

Deconstructing cellular senescence in bone and beyond
por: Hofbauer, Lorenz C., et al.
Publicado: (2023)

The Bone Morphogenetic Protein Pathway: The Osteoclastic Perspective
por: Lademann, Franziska, et al.
Publicado: (2020)

Aberrant Bone Homeostasis in AML Is Associated with Activated Oncogenic FLT3-Dependent Cytokine Networks
por: Bär, Isabel, et al.
Publicado: (2020)

Irisin and Bone in Sickness and in Health: A Narrative Review of the Literature
por: Tsourdi, Elena, et al.
Publicado: (2022)

Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties
por: Picke, Ann-Kristin, et al.
Publicado: (2019)

Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
por: Hildebrandt, Susanne, et al.
Publicado: (2018)

Author Correction: Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
por: Hildebrandt, Susanne, et al.
Publicado: (2020)

Effect of Anti-Osteoporotic Treatments on Circulating and Bone MicroRNA Patterns in Osteopenic ZDF Rats
por: Carro Vázquez, David, et al.
Publicado: (2022)

SAT-586 Cold-Acclimation Prevents the Onset of Glucocorticoid-Induced Adipose Dysfunction in Male Mice
por: Gado, Manuel M, et al.
Publicado: (2020)

SUN-LB65 Circulating Micrornas Linked to Bone Metabolism Are Affected by Sequential Anti Osteoporotic Treatment in Postmenopausal Osteoporosis
por: Yavropoulou, Maria, et al.
Publicado: (2020)

Regulation of sclerostin in glucocorticoid-induced osteoporosis (GIO) in mice and humans
por: Thiele, Sylvia, et al.
Publicado: (2019)

Concurrent antitumor and bone-protective effects of everolimus in osteotropic breast cancer
por: Browne, Andrew J., et al.
Publicado: (2017)

Bone Marrow Adipocytes: A Link between Obesity and Bone Cancer
por: Reagan, Michaela R., et al.
Publicado: (2021)

Designation of a Novel DKK1 Multiepitope DNA Vaccine and Inhibition of Bone Loss in Collagen-Induced Arthritic Mice
por: Zhang, Xiaoqing, et al.
Publicado: (2015)

Targeting syndecan-1 in breast cancer inhibits osteoclast functions through up-regulation of osteoprotegerin
por: Benad-Mehner, Peggy, et al.
Publicado: (2013)

Roles of Dkk2 in the Linkage from Muscle to Bone during Mechanical Unloading in Mice
por: Kawao, Naoyuki, et al.
Publicado: (2020)

DKK1 and Kremen Expression Predicts the Osteoblastic Response to Bone Metastasis()
por: Clines, Katrina L., et al.
Publicado: (2018)

Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice
por: Wan, Daqian, et al.
Publicado: (2021)

Erythropoietin Mediated Bone Loss in Mice Is Dose-Dependent and Mostly Irreversible
por: Kolomansky, Albert, et al.
Publicado: (2020)

Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma
por: Wang, Y, et al.
Publicado: (2017)

Rodent Models of Spondyloarthritis Have Decreased White and Bone Marrow Adipose Tissue Depots
por: Furesi, Giulia, et al.
Publicado: (2021)

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice
por: Beghini, Marianna, et al.
Publicado: (2021)

SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease
por: Mason, James J., et al.
Publicado: (2010)

COMBINING SCLEROSTIN AND DKK1 INHIBITORS TO IMPROVE BONE PROPERTIES IN THE AGED SKELETON
por: Choi, Roy, et al.
Publicado: (2022)

From bone to breast and back - the bone cytokine RANKL and breast cancer
por: Hofbauer, Lorenz C, et al.
Publicado: (2011)

Obesity-Induced Changes in Bone Marrow Homeostasis
por: Benova, Andrea, et al.
Publicado: (2020)

The role of bone marrow adipocytes in bone metastasis
por: Morris, Emma V., et al.
Publicado: (2016)

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice
por: Maass, Thorsten, et al.
Publicado: (2015)

Prednisone prevents particle induced bone loss in the calvaria mouse model
por: Schündeln, Michael M., et al.
Publicado: (2021)

DNA methylation of DKK‐1 may correlate with pathological bone formation in ankylosing spondylitis
por: Zou, Yu‐Cong, et al.
Publicado: (2023)

Obese Adipocytes Have Altered Redox Homeostasis with Metabolic Consequences
por: Cinti, Saverio
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0veu20s4j945t6an599uko5t2e