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Ultrasonic-induced synthesis of novel diverse arylidenes via Knoevenagel condensation reaction. Antitumor, QSAR, docking and DFT assessment

A series of arylidenes derivatives was synthesized under ultrasonic methodology via Knoevenagel condensation reaction of cyanoacetohydrazide derivative with the appropriate aldehydes and/or ketone. The anticancer properties of the newly synthesized compounds were tested against four different human...

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Detalles Bibliográficos
Autores principales: El-Sayed Ebead, Eman, Aboelnaga, Asmaa, Nassar, Ekhlass, Naguib, Mohamed M., Ismail, Mahmoud F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563797/
https://www.ncbi.nlm.nih.gov/pubmed/37822658
http://dx.doi.org/10.1039/d3ra05799b