Cargando…

Qualifying a Novel Clinical Trial Endpoint (iBOX) Predictive of Long-Term Kidney Transplant Outcomes

New immunosuppressive therapies that improve long-term graft survival are needed in kidney transplant. Critical Path Institute’s Transplant Therapeutics Consortium received a qualification opinion for the iBOX Scoring System as a novel secondary efficacy endpoint for kidney transplant clinical trial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klein, Amanda, Loupy, Alexandre, Stegall, Mark, Helanterä, Ilkka, Kosinski, Luke, Frey, Eric, Aubert, Olivier, Divard, Gillian, Newell, Kenneth, Meier-Kriesche, Herwig-Ulf, Mannon, Roslyn, Dumortier, Thomas, Aggarwal, Varun, Podichetty, Jagdeep T., O’Doherty, Inish, Gaber, Ahmed Osama, Fitzsimmons, William E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Health Archive
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563802/ https://www.ncbi.nlm.nih.gov/pubmed/37822449 http://dx.doi.org/10.3389/ti.2023.11951

Ejemplares similares

Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study
por: Aubert, Olivier, et al.
Publicado: (2021)

Longitudinal estimated glomerular filtration rate (eGFR) modeling in long‐term renal function to inform clinical trial design in kidney transplantation
por: Kosinski, Luke, et al.
Publicado: (2023)

The impact of blended learning on students using the IBOX platform: Initial perspectives of teachers
por: Barfi, Kwaku Anhwere, et al.
Publicado: (2023)

Leveraging Real‐World Data for EMA Qualification of a Model‐Based Biomarker Tool to Optimize Type‐1 Diabetes Prevention Studies
por: Podichetty, Jagdeep T., et al.
Publicado: (2022)

Disease progression joint model predicts time to type 1 diabetes onset: Optimizing future type 1 diabetes prevention studies
por: Morales, Juan Francisco, et al.
Publicado: (2023)

Recommendations for the development of rare disease drugs using the accelerated approval pathway and for qualifying biomarkers as primary endpoints
por: Kakkis, Emil D, et al.
Publicado: (2015)

How can natural language processing help model informed drug development?: a review
por: Bhatnagar, Roopal, et al.
Publicado: (2022)

Is It Time for Operation Warp Speed in Transplant Research?
por: Mannon, Roslyn B.
Publicado: (2020)

Surrogate Endpoints for Late Kidney Transplantation Failure
por: Naesens, Maarten, et al.
Publicado: (2022)

Allograft Function as Endpoint for Clinical Trials in Kidney Transplantation
por: Hilbrands, Luuk, et al.
Publicado: (2022)

From the Cradle to the Grave: The Life Cycle of Gender Disparities in Kidney Care
por: Lalji, Rowena, et al.
Publicado: (2022)

The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell–mediated rejection, antibody‐mediated rejection, and prospects for integrative endpoints for next‐generation clinical trials
por: Haas, M., et al.
Publicado: (2018)

Get qualified
por: Smith, Kevin
Publicado: (2017)

Get qualified
por: Smith, Kevin
Publicado: (2016)

Qualifying for Practice
Publicado: (1896)

The Qualified Dentist
Publicado: (1897)

The feasibility of genome-scale biological network inference using Graphics Processing Units
por: Thiagarajan, Raghuram, et al.
Publicado: (2017)

Long-Term Follow-Up of a Phase III Clinical Trial Comparing Tacrolimus Extended-Release/MMF, Tacrolimus/MMF, and Cyclosporine/MMF in De Novo Kidney Transplant Recipients
por: Silva, Hélio Tedesco, et al.
Publicado: (2014)

Rationale for Surrogate Endpoints and Conditional Marketing Authorization of New Therapies for Kidney Transplantation
por: Naesens, Maarten, et al.
Publicado: (2022)

Quacks versus Qualified
por: Bhattacharjee, Jagadish
Publicado: (1932)

The Claims of Qualified Dentistry
Publicado: (1918)

Opportunities for the Qualified Practitioner
Publicado: (1907)

The Registration of Qualified Nurses
por: Steele, J. C.
Publicado: (1887)

"Qualified Nurses" and Their Qualifications
Publicado: (1921)

Qualified Practitioners in Belgium
Publicado: (1895)

Socio-demographic predictors of structural empowerment among newly qualified nurses: Findings from an international survey
por: Mansour, Mansour, et al.
Publicado: (2021)

Who qualifies to be a bioinformatician?
por: Vincent, Antony T., et al.
Publicado: (2015)

The List of Qualified Medical Practitioners
por: Bomford, G.
Publicado: (1902)

An M.D. Self-Qualified
Publicado: (1892)

Practicing With Uncertainty: Kidney Transplantation During the COVID-19 Pandemic
por: Lentine, Krista L., et al.
Publicado: (2021)

Association of Procurement Time With Pancreas Transplant Outcomes in Brain-Dead Donors
por: Eerola, Verner, et al.
Publicado: (2023)

Proposed Definitions of T Cell-Mediated Rejection and Tubulointerstitial Inflammation as Clinical Trial Endpoints in Kidney Transplantation
por: Seron, Daniel, et al.
Publicado: (2022)

Proposed Definitions of Antibody-Mediated Rejection for Use as a Clinical Trial Endpoint in Kidney Transplantation
por: Roufosse, Candice, et al.
Publicado: (2022)

Participation in the Qualified Medicare Beneficiary Program
por: Neumann, Peter J., et al.
Publicado: (1995)

Receptivity to Bariatric Surgery in Qualified Patients
por: Fung, Michael, et al.
Publicado: (2016)

The Need for Young Qualified Medical Men
por: MacAlister, Donald
Publicado: (1914)

What It Offers to the Newly-Qualified and Others
Publicado: (1920)

Qualifying and quantifying the precision medicine rhetoric
por: Lee, Jasmine, et al.
Publicado: (2019)

Severity as a moral qualifier of malady
por: Solberg, Carl Tollef, et al.
Publicado: (2023)

SARS‐CoV‐2 vaccination in solid‐organ transplant recipients: What the clinician needs to know
por: Giannella, Maddalena, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7n7bhbj9vtb742ltvqucivm6ch