Cargando…

Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial

BACKGROUND: A randomized clinical trial (HiFlo-COVID-19 Trial) showed that among patients with severe COVID-19, treatment with high-flow oxygen therapy (HFOT) significantly reduced the need for invasive mechanical ventilation support and time for clinical recovery compared with conventional oxygen t...

Descripción completa

Detalles Bibliográficos
Autores principales: Prada, Sergio I, Garcia-Garcia, Maria P, Ospina-Tascón, Gustavo A, Rosselli, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564115/
https://www.ncbi.nlm.nih.gov/pubmed/37822790
http://dx.doi.org/10.2147/CEOR.S412087
_version_ 1785118436230168576
author Prada, Sergio I
Garcia-Garcia, Maria P
Ospina-Tascón, Gustavo A
Rosselli, Diego
author_facet Prada, Sergio I
Garcia-Garcia, Maria P
Ospina-Tascón, Gustavo A
Rosselli, Diego
author_sort Prada, Sergio I
collection PubMed
description BACKGROUND: A randomized clinical trial (HiFlo-COVID-19 Trial) showed that among patients with severe COVID-19, treatment with high-flow oxygen therapy (HFOT) significantly reduced the need for invasive mechanical ventilation support and time for clinical recovery compared with conventional oxygen therapy (COT). However, the cost of this strategy is unknown. OBJECTIVE: We examined total cost of HFOT treatment compared with COT in real-world setting. METHODS: We conducted a post-trial-based cost analysis from the perspective of a managed competition healthcare system, using actual records of billed costs. Cost categories include general ward, intensive care unit, procedures, imaging, laboratories, medications, supplies, and others. RESULTS: A total of 188 participants (mean age 60, 33% female) were included. Average costs (and standard deviation) in the HFOT group were USD $7992 (7394) and in the COT group USD $ 10,190 (9402). Differences, however, did not reach statistical significance (P=0.093). However, resource use was always less costly for the HNFO group, with an overall percentage decrease of 27%. Two categories make up 72% of all savings: medications (41%) and intensive care unit (31%). CONCLUSION: For patients in ICU with severe COVID-19 the cost of treatment with HFOT as compared to COT is likely to be cost-saving due to less use of medications and length of stay in ICU.
format Online
Article
Text
id pubmed-10564115
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-105641152023-10-11 Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial Prada, Sergio I Garcia-Garcia, Maria P Ospina-Tascón, Gustavo A Rosselli, Diego Clinicoecon Outcomes Res Original Research BACKGROUND: A randomized clinical trial (HiFlo-COVID-19 Trial) showed that among patients with severe COVID-19, treatment with high-flow oxygen therapy (HFOT) significantly reduced the need for invasive mechanical ventilation support and time for clinical recovery compared with conventional oxygen therapy (COT). However, the cost of this strategy is unknown. OBJECTIVE: We examined total cost of HFOT treatment compared with COT in real-world setting. METHODS: We conducted a post-trial-based cost analysis from the perspective of a managed competition healthcare system, using actual records of billed costs. Cost categories include general ward, intensive care unit, procedures, imaging, laboratories, medications, supplies, and others. RESULTS: A total of 188 participants (mean age 60, 33% female) were included. Average costs (and standard deviation) in the HFOT group were USD $7992 (7394) and in the COT group USD $ 10,190 (9402). Differences, however, did not reach statistical significance (P=0.093). However, resource use was always less costly for the HNFO group, with an overall percentage decrease of 27%. Two categories make up 72% of all savings: medications (41%) and intensive care unit (31%). CONCLUSION: For patients in ICU with severe COVID-19 the cost of treatment with HFOT as compared to COT is likely to be cost-saving due to less use of medications and length of stay in ICU. Dove 2023-10-06 /pmc/articles/PMC10564115/ /pubmed/37822790 http://dx.doi.org/10.2147/CEOR.S412087 Text en © 2023 Prada et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Prada, Sergio I
Garcia-Garcia, Maria P
Ospina-Tascón, Gustavo A
Rosselli, Diego
Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title_full Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title_fullStr Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title_full_unstemmed Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title_short Cost Analysis of High-Flow Oxygen Therapy Compared with Conventional Oxygen Therapy in Severe COVID-19 in Colombia: Data from a Randomized Clinical Trial
title_sort cost analysis of high-flow oxygen therapy compared with conventional oxygen therapy in severe covid-19 in colombia: data from a randomized clinical trial
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564115/
https://www.ncbi.nlm.nih.gov/pubmed/37822790
http://dx.doi.org/10.2147/CEOR.S412087
work_keys_str_mv AT pradasergioi costanalysisofhighflowoxygentherapycomparedwithconventionaloxygentherapyinseverecovid19incolombiadatafromarandomizedclinicaltrial
AT garciagarciamariap costanalysisofhighflowoxygentherapycomparedwithconventionaloxygentherapyinseverecovid19incolombiadatafromarandomizedclinicaltrial
AT ospinatascongustavoa costanalysisofhighflowoxygentherapycomparedwithconventionaloxygentherapyinseverecovid19incolombiadatafromarandomizedclinicaltrial
AT rossellidiego costanalysisofhighflowoxygentherapycomparedwithconventionaloxygentherapyinseverecovid19incolombiadatafromarandomizedclinicaltrial