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Deep coverage and quantification of the bone proteome provides enhanced opportunities for new discoveries in skeletal biology and disease

Dysregulation of cell signaling in chondrocytes and in bone cells, such as osteocytes, osteoblasts, osteoclasts, and an elevated burden of senescent cells in cartilage and bone, are implicated in osteoarthritis (OA). Mass spectrometric analyses provides a crucial molecular tool-kit to understand com...

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Detalles Bibliográficos
Autores principales: Rose, Jacob P., Schurman, Charles A., King, Christina D., Bons, Joanna, Patel, Sandip K., Burton, Jordan B., O’Broin, Amy, Alliston, Tamara, Schilling, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564166/
https://www.ncbi.nlm.nih.gov/pubmed/37816044
http://dx.doi.org/10.1371/journal.pone.0292268

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