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Deep coverage and quantification of the bone proteome provides enhanced opportunities for new discoveries in skeletal biology and disease
Dysregulation of cell signaling in chondrocytes and in bone cells, such as osteocytes, osteoblasts, osteoclasts, and an elevated burden of senescent cells in cartilage and bone, are implicated in osteoarthritis (OA). Mass spectrometric analyses provides a crucial molecular tool-kit to understand com...
Autores principales: | Rose, Jacob P., Schurman, Charles A., King, Christina D., Bons, Joanna, Patel, Sandip K., Burton, Jordan B., O’Broin, Amy, Alliston, Tamara, Schilling, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564166/ https://www.ncbi.nlm.nih.gov/pubmed/37816044 http://dx.doi.org/10.1371/journal.pone.0292268 |
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