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Possible effect of mutations on serological detection of Borrelia burgdorferi sensu stricto ospC major groups: An in-silico study

The outer surface protein C (OspC) of the agent of Lyme disease, Borrelia burgdorferi sensu stricto, is a major lipoprotein surface-expressed during early-phase human infections. Antibodies to OspC are used in serological diagnoses. This study explored the hypothesis that serological test sensitivit...

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Detalles Bibliográficos
Autores principales: Mechai, Samir, Coatsworth, Heather, Ogden, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564231/
https://www.ncbi.nlm.nih.gov/pubmed/37815990
http://dx.doi.org/10.1371/journal.pone.0292741