An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8(+) T cell magnitude and short-lived differentiation status

Before initiation of antiretroviral therapy (ART), HIV-specific CD8(+) T cells are dysfunctional and short lived. To better understand the relationship between the HIV reservoir in CD4(+) T cells and the magnitude and differentiation status of HIV-specific CD8(+) T cells, we investigated these cells...

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Detalles Bibliográficos
Autores principales: Takata, Hiroshi, Mitchell, Julie L., Pacheco, Julian, Pagliuzza, Amélie, Pinyakorn, Suteeraporn, Buranapraditkun, Supranee, Sacdalan, Carlo, Leyre, Louise, Nathanson, Sam, Kakazu, Juyeon C., Intasan, Jintana, Prueksakaew, Peeriya, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Haddad, Elias K., Rolland, Morgane, Tovanabutra, Sodsai, Vasan, Sandhya, Hsu, Denise C., Chomont, Nicolas, Trautmann, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564289/
https://www.ncbi.nlm.nih.gov/pubmed/37708852
http://dx.doi.org/10.1016/j.chom.2023.08.012

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