Cargando…
NOTCH2 gene mutation and gamma-secretase inhibitor in mediating the malignancy of ovarian cancer
The carcinogenic mechanisms by which serous ovarian cancer (OC) occurs remain to be explored. Currently, we have conducted whole-exome sequencing (WES) and targeted deep sequencing to validate new molecular markers, including NOTCH2, that impede the progression of cell malignancy in ovarian cancer (...
Autores principales: | Wang, Wenjing, Liu, Ruiqian, Liao, Wei, Ji, Landie, Mei, Jie, Su, Dan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564443/ https://www.ncbi.nlm.nih.gov/pubmed/37728427 http://dx.doi.org/10.18632/aging.205045 |
Ejemplares similares
-
Gamma secretase inhibitors of Notch signaling
por: Olsauskas-Kuprys, Roma, et al.
Publicado: (2013) -
Gamma Secretase Inhibitors as Potential Therapeutic Targets for Notch Signaling in Uterine Leiomyosarcoma
por: Abedin, Yasmin, et al.
Publicado: (2022) -
Inhibition of gamma-secretase in Notch1 signaling pathway as a novel treatment for ovarian cancer
por: Feng, Zhaoyi, et al.
Publicado: (2016) -
Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification
por: Wang, Zheng, et al.
Publicado: (2023) -
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
por: O'Neil, Jennifer, et al.
Publicado: (2007)