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Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives

Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally...

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Detalles Bibliográficos
Autores principales: Jen, Rachel, Ellis, Colin, Kaminska, Marta, Road, Jeremy, Ayas, Najib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564575/
https://www.ncbi.nlm.nih.gov/pubmed/37822670
http://dx.doi.org/10.1155/2023/8691539
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author Jen, Rachel
Ellis, Colin
Kaminska, Marta
Road, Jeremy
Ayas, Najib
author_facet Jen, Rachel
Ellis, Colin
Kaminska, Marta
Road, Jeremy
Ayas, Najib
author_sort Jen, Rachel
collection PubMed
description Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO(2)) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach.
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spelling pubmed-105645752023-10-11 Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives Jen, Rachel Ellis, Colin Kaminska, Marta Road, Jeremy Ayas, Najib Can Respir J Review Article Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO(2)) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach. Hindawi 2023-10-03 /pmc/articles/PMC10564575/ /pubmed/37822670 http://dx.doi.org/10.1155/2023/8691539 Text en Copyright © 2023 Rachel Jen et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Jen, Rachel
Ellis, Colin
Kaminska, Marta
Road, Jeremy
Ayas, Najib
Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title_full Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title_fullStr Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title_full_unstemmed Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title_short Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
title_sort noninvasive home mechanical ventilation for stable hypercapnic copd: a clinical respiratory review from canadian perspectives
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564575/
https://www.ncbi.nlm.nih.gov/pubmed/37822670
http://dx.doi.org/10.1155/2023/8691539
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