Cargando…
Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564575/ https://www.ncbi.nlm.nih.gov/pubmed/37822670 http://dx.doi.org/10.1155/2023/8691539 |
_version_ | 1785118507404361728 |
---|---|
author | Jen, Rachel Ellis, Colin Kaminska, Marta Road, Jeremy Ayas, Najib |
author_facet | Jen, Rachel Ellis, Colin Kaminska, Marta Road, Jeremy Ayas, Najib |
author_sort | Jen, Rachel |
collection | PubMed |
description | Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO(2)) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach. |
format | Online Article Text |
id | pubmed-10564575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-105645752023-10-11 Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives Jen, Rachel Ellis, Colin Kaminska, Marta Road, Jeremy Ayas, Najib Can Respir J Review Article Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO(2)) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach. Hindawi 2023-10-03 /pmc/articles/PMC10564575/ /pubmed/37822670 http://dx.doi.org/10.1155/2023/8691539 Text en Copyright © 2023 Rachel Jen et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Jen, Rachel Ellis, Colin Kaminska, Marta Road, Jeremy Ayas, Najib Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title_full | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title_fullStr | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title_full_unstemmed | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title_short | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
title_sort | noninvasive home mechanical ventilation for stable hypercapnic copd: a clinical respiratory review from canadian perspectives |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564575/ https://www.ncbi.nlm.nih.gov/pubmed/37822670 http://dx.doi.org/10.1155/2023/8691539 |
work_keys_str_mv | AT jenrachel noninvasivehomemechanicalventilationforstablehypercapniccopdaclinicalrespiratoryreviewfromcanadianperspectives AT elliscolin noninvasivehomemechanicalventilationforstablehypercapniccopdaclinicalrespiratoryreviewfromcanadianperspectives AT kaminskamarta noninvasivehomemechanicalventilationforstablehypercapniccopdaclinicalrespiratoryreviewfromcanadianperspectives AT roadjeremy noninvasivehomemechanicalventilationforstablehypercapniccopdaclinicalrespiratoryreviewfromcanadianperspectives AT ayasnajib noninvasivehomemechanicalventilationforstablehypercapniccopdaclinicalrespiratoryreviewfromcanadianperspectives |