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Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study
Aim: We examined the association between the carotid intima medica thickness (cIMT) and risk factors for atherosclerosis based on the Japan Atherosclerosis Society 2022 Atherosclerosis Prevention Guideline. Methods: Using data from the Tohoku Medical Megabank Community-based Cohort Study, we perform...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Atherosclerosis Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564640/ https://www.ncbi.nlm.nih.gov/pubmed/36775331 http://dx.doi.org/10.5551/jat.64039 |
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author | Takase, Masato Nakaya, Naoki Nakamura, Tomohiro Kogure, Mana Hatanaka, Rieko Nakaya, Kumi Chiba, Ippei Kanno, Ikumi Nochioka, Kotaro Tsuchiya, Naho Hirata, Takumi Hamanaka, Yohei Sugawara, Junichi Kobayashi, Tomoko Fuse, Nobuo Uruno, Akira Kodama, Eiichi N Kuriyama, Shinichi Tsuji, Ichiro Hozawa, Atsushi |
author_facet | Takase, Masato Nakaya, Naoki Nakamura, Tomohiro Kogure, Mana Hatanaka, Rieko Nakaya, Kumi Chiba, Ippei Kanno, Ikumi Nochioka, Kotaro Tsuchiya, Naho Hirata, Takumi Hamanaka, Yohei Sugawara, Junichi Kobayashi, Tomoko Fuse, Nobuo Uruno, Akira Kodama, Eiichi N Kuriyama, Shinichi Tsuji, Ichiro Hozawa, Atsushi |
author_sort | Takase, Masato |
collection | PubMed |
description | Aim: We examined the association between the carotid intima medica thickness (cIMT) and risk factors for atherosclerosis based on the Japan Atherosclerosis Society 2022 Atherosclerosis Prevention Guideline. Methods: Using data from the Tohoku Medical Megabank Community-based Cohort Study, we performed a cross-sectional study that enrolled 13,366 participants (age ≥ 20 years) with an analysis of covariance to assess associations between cIMT and risk factors for atherosclerosis. The maximum common carotid artery was measured using high-resolution B-mode ultrasound. Analysis was conducted in the model adjusted for age, sex, smoking status, drinking status, body mass index (BMI), systolic blood pressure (SBP), glycated hemoglobin (HbA1c), high-density lipoprotein-cholesterol (HDL-C), non-high-density lipoprotein-cholesterol (non-HDL-C), and height. Results: In this study cohort, the average age and cIMT were 57.3 (13.8) years and 0.61 (0.13) mm, respectively, which included 3,988 males (29.8%). Males had a higher cIMT than did the females. Age, height, BMI, SBP, HbA1c, and non-HDL-C were positively associated with cIMT. HDL-C was inversely associated with cIMT. Compared with never drinkers, current drinkers (≥ 46.0 g/day) had a significantly decreased cIMT. Conclusions: The cIMT was associated with atherosclerosis risk factors including age, sex, BMI, SBP, HbA1c, non-HDL-C, and HDL-C, and adequate control of risks in high-risk individuals might be required to prevent atherosclerotic cardiovascular diseases. |
format | Online Article Text |
id | pubmed-10564640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Japan Atherosclerosis Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-105646402023-10-12 Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study Takase, Masato Nakaya, Naoki Nakamura, Tomohiro Kogure, Mana Hatanaka, Rieko Nakaya, Kumi Chiba, Ippei Kanno, Ikumi Nochioka, Kotaro Tsuchiya, Naho Hirata, Takumi Hamanaka, Yohei Sugawara, Junichi Kobayashi, Tomoko Fuse, Nobuo Uruno, Akira Kodama, Eiichi N Kuriyama, Shinichi Tsuji, Ichiro Hozawa, Atsushi J Atheroscler Thromb Original Article Aim: We examined the association between the carotid intima medica thickness (cIMT) and risk factors for atherosclerosis based on the Japan Atherosclerosis Society 2022 Atherosclerosis Prevention Guideline. Methods: Using data from the Tohoku Medical Megabank Community-based Cohort Study, we performed a cross-sectional study that enrolled 13,366 participants (age ≥ 20 years) with an analysis of covariance to assess associations between cIMT and risk factors for atherosclerosis. The maximum common carotid artery was measured using high-resolution B-mode ultrasound. Analysis was conducted in the model adjusted for age, sex, smoking status, drinking status, body mass index (BMI), systolic blood pressure (SBP), glycated hemoglobin (HbA1c), high-density lipoprotein-cholesterol (HDL-C), non-high-density lipoprotein-cholesterol (non-HDL-C), and height. Results: In this study cohort, the average age and cIMT were 57.3 (13.8) years and 0.61 (0.13) mm, respectively, which included 3,988 males (29.8%). Males had a higher cIMT than did the females. Age, height, BMI, SBP, HbA1c, and non-HDL-C were positively associated with cIMT. HDL-C was inversely associated with cIMT. Compared with never drinkers, current drinkers (≥ 46.0 g/day) had a significantly decreased cIMT. Conclusions: The cIMT was associated with atherosclerosis risk factors including age, sex, BMI, SBP, HbA1c, non-HDL-C, and HDL-C, and adequate control of risks in high-risk individuals might be required to prevent atherosclerotic cardiovascular diseases. Japan Atherosclerosis Society 2023-10-01 2023-02-11 /pmc/articles/PMC10564640/ /pubmed/36775331 http://dx.doi.org/10.5551/jat.64039 Text en 2023 Japan Atherosclerosis Society https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) |
spellingShingle | Original Article Takase, Masato Nakaya, Naoki Nakamura, Tomohiro Kogure, Mana Hatanaka, Rieko Nakaya, Kumi Chiba, Ippei Kanno, Ikumi Nochioka, Kotaro Tsuchiya, Naho Hirata, Takumi Hamanaka, Yohei Sugawara, Junichi Kobayashi, Tomoko Fuse, Nobuo Uruno, Akira Kodama, Eiichi N Kuriyama, Shinichi Tsuji, Ichiro Hozawa, Atsushi Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title | Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title_full | Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title_fullStr | Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title_full_unstemmed | Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title_short | Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study |
title_sort | carotid intima media thickness and risk factor for atherosclerosis: tohoku medical megabank community-based cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564640/ https://www.ncbi.nlm.nih.gov/pubmed/36775331 http://dx.doi.org/10.5551/jat.64039 |
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