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Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect

Colorectal cancer (CRC) is a prevalent malignancy worldwide and is associated with a high mortality rate. Changes in bioenergy metabolism, such as the Warburg effect, are often observed in CRC. Aldolase B (ALDOB) has been identified as a potential regulator of these changes, but its exact role in CR...

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Detalles Bibliográficos
Autores principales: Chu, Yu-De, Cheng, Li-Chun, Lim, Siew-Na, Lai, Ming-Wei, Yeh, Chau-Ting, Lin, Wey-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564793/
https://www.ncbi.nlm.nih.gov/pubmed/37816733
http://dx.doi.org/10.1038/s41419-023-06187-z