Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis

In multiple sclerosis (MS), sustained inflammatory activity can be visualized by iron-sensitive magnetic resonance imaging (MRI) at the edges of chronic lesions. These paramagnetic rim lesions (PRLs) are associated with clinical worsening, although the cell type-specific and molecular pathways of ir...

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Detalles Bibliográficos
Autores principales: Hofmann, Annika, Krajnc, Nik, Dal-Bianco, Assunta, Riedl, Christian J., Zrzavy, Tobias, Lerma-Martin, Celia, Kasprian, Gregor, Weber, Claudia E., Pezzini, Francesco, Leutmezer, Fritz, Rommer, Paulus, Bsteh, Gabriel, Platten, Michael, Gass, Achim, Berger, Thomas, Eisele, Philipp, Magliozzi, Roberta, Schirmer, Lucas, Hametner, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564819/
https://www.ncbi.nlm.nih.gov/pubmed/37715818
http://dx.doi.org/10.1007/s00401-023-02627-4

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