HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

HIV-1 infection causes severe alterations of gut mucosa, microbiota and immune system, which can be curbed by early antiretroviral therapy. Here, we investigate how treatment timing affects intestinal memory B-cell and plasmablast repertoires of HIV-1-infected humans. We show that only class-switche...

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Detalles Bibliográficos
Autores principales: Planchais, Cyril, Molinos-Albert, Luis M., Rosenbaum, Pierre, Hieu, Thierry, Kanyavuz, Alexia, Clermont, Dominique, Prazuck, Thierry, Lefrou, Laurent, Dimitrov, Jordan D., Hüe, Sophie, Hocqueloux, Laurent, Mouquet, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564866/
https://www.ncbi.nlm.nih.gov/pubmed/37816704
http://dx.doi.org/10.1038/s41467-023-42027-6

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