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Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission

Humanized mice have been used to study human immunodeficiency virus type 1 (HIV-1) transmission, pathogenesis, and treatment. The ability of pediatric thymus tissue implanted either in the leg (Leg PedThy) or under the renal capsule (Renal PedThy) with allogeneic CD34+ hematopoietic cells (HSCs) in...

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Detalles Bibliográficos
Autores principales:	Roy, Chandra N., Shu, Sherry T., Kline, Christopher, Rigatti, Lora, Smithgall, Thomas E., Ambrose, Zandrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564933/ https://www.ncbi.nlm.nih.gov/pubmed/37816950 http://dx.doi.org/10.1038/s41598-023-44366-2

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