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FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms

Appropriate cytoskeletal organization is essential for vascular smooth muscle cell (VSMC) conditions such as hypertension. This study identifies FXR1 as a key protein linking cytoskeletal dynamics with mRNA stability. RNA immunoprecipitation sequencing (RIP-seq) in human VSMCs identifies that FXR1 b...

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Detalles Bibliográficos
Autores principales:	St. Paul, Amanda, Corbett, Cali, Peluzzo, Amanda, Kelemen, Sheri, Okune, Rachael, Haines, Dale S., Preston, Kyle, Eguchi, Satoru, Autieri, Michael V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564969/ https://www.ncbi.nlm.nih.gov/pubmed/37043351 http://dx.doi.org/10.1016/j.celrep.2023.112381

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