Cargando…

MFSD2A potentiates gastric cancer response to anti‐PD‐1 immunotherapy by reprogramming the tumor microenvironment to activate T cell response

BACKGROUND: The efficacy of anti‐programmed cell death protein 1 (PD‐1) immunotherapy in various cancers, including gastric cancer (GC), needs to be potentiated by more effective targeting to enhance therapeutic efficacy or identifying accurate biomarkers to predict clinical responses. Here, we atte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Bin, Wang, Chun‐Mei, Wu, Hao‐Xiang, Wang, Feng, Chai, Yang‐Yang, Hu, Ye, Wang, Bing‐Jing, Yu, Zhou, Xia, Rong‐Hua, Xu, Rui‐Hua, Cao, Xue‐Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565382/ https://www.ncbi.nlm.nih.gov/pubmed/37539769 http://dx.doi.org/10.1002/cac2.12476

Ejemplares similares

Impacts and mechanisms of metabolic reprogramming of tumor microenvironment for immunotherapy in gastric cancer
por: Zhao, Lin, et al.
Publicado: (2022)

Immunosuppressive mechanisms of oncofetal reprogramming in the tumor microenvironment: implications in immunotherapy response
por: Currenti, Jennifer, et al.
Publicado: (2023)

Cuproptosis-Mediated Patterns Characterized by Distinct Tumor Microenvironment and Predicted the Immunotherapy Response for Gastric Cancer
por: Wang, Xiang-Xu, et al.
Publicado: (2023)

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme
por: Li, Yingzhong, et al.
Publicado: (2020)

Polypyrrole Nanoenzymes as Tumor Microenvironment Modulators to Reprogram Macrophage and Potentiate Immunotherapy
por: Zeng, Weiwei, et al.
Publicado: (2022)

Review of biomarkers for response to immunotherapy in HNSCC microenvironment
por: Chen, Shaoshi, et al.
Publicado: (2023)

Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
por: Lekholm, Emilia, et al.
Publicado: (2017)

Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer
por: Huang, Weicai, et al.
Publicado: (2022)

Tumor microenvironment responsive metal nanoparticles in cancer immunotherapy
por: Yang, Rou, et al.
Publicado: (2023)

Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy
por: Jiang, Hong, et al.
Publicado: (2015)

The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake
por: Perland, Emelie, et al.
Publicado: (2016)

Epigenetic reprogramming of Runx3 reinforces CD8 + T-cell function and improves the clinical response to immunotherapy
por: Liu, Zongzhi, et al.
Publicado: (2023)

Combining single-cell sequencing data to construct a prognostic signature to predict survival, immune microenvironment, and immunotherapy response in gastric cancer patients
por: Hu, Bo, et al.
Publicado: (2022)

Novel MFSD8 Variants in a Chinese Family with Nonsyndromic Macular Dystrophy
por: Xiang, Qin, et al.
Publicado: (2021)

Mfsd2a (Major Facilitator Superfamily Domain Containing 2a) Attenuates Intracerebral Hemorrhage–Induced Blood–Brain Barrier Disruption by Inhibiting Vesicular Transcytosis
por: Yang, Yuan‐Rui, et al.
Publicado: (2017)

MFSD12 affects glycosphingolipid metabolism by modulating lysosome homeostasis
por: Hong, Yun, et al.
Publicado: (2022)

A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment
por: Kuo, Cheng-Liang, et al.
Publicado: (2022)

Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy
por: Saeed, Madiha, et al.
Publicado: (2019)

Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice
por: Perland, Emelie, et al.
Publicado: (2017)

Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer
por: Sung, Ji‐Yong, et al.
Publicado: (2022)

Immunotherapy response and microenvironment provide biomarkers of immunotherapy options for patients with lung adenocarcinoma
por: Zhan, Xue, et al.
Publicado: (2022)

Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy
por: Huang, Ju, et al.
Publicado: (2023)

An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer
por: Sun, Yanan, et al.
Publicado: (2022)

Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma
por: Ng, Harry Ho Man, et al.
Publicado: (2020)

The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis
por: Perland, Emelie, et al.
Publicado: (2016)

Correction: Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice
por: Perland, Emelie, et al.
Publicado: (2018)

Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy
por: Sánchez-Campillo, María, et al.
Publicado: (2020)

High-fat treatment prevents postoperative cognitive dysfunction in a hyperlipidemia model by protecting the blood-brain barrier via Mfsd2a-related signaling
por: Zhang, Xiao-Ping, et al.
Publicado: (2019)

Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations
por: Colton, Madyson, et al.
Publicado: (2020)

The role of lipid metabolic reprogramming in tumor microenvironment
por: Yang, Kai, et al.
Publicado: (2023)

N6-Methyladenine-Related Signature for Immune Microenvironment and Response to Immunotherapy in Hepatocellular Carcinoma
por: Ren, Shao-hua, et al.
Publicado: (2022)

MFSD12 mediates the import of cysteine into melanosomes and lysosomes
por: Adelmann, Charles H., et al.
Publicado: (2020)

The Role of Mfsd2a in Nervous System Diseases
por: Huang, Bei, et al.
Publicado: (2021)

Metabolic Reprogramming in Gastric Cancer: Trojan Horse Effect
por: Bin, Yu-Ling, et al.
Publicado: (2022)

The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis
por: Wong, Bernice H., et al.
Publicado: (2022)

Sono-Immunotherapy Mediated Controllable Composite Nano Fluorescent Probes Reprogram the Immune Microenvironment of Hepatocellular Carcinoma
por: Chen, Yichi, et al.
Publicado: (2023)

Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer
por: Ruan, Dan-Yun, et al.
Publicado: (2021)

Immunotherapy of Cancer: Reprogramming Tumor-Immune Crosstalk
por: Payne, Kyle K., et al.
Publicado: (2012)

Predicting response to immunotherapy in gastric cancer via assessing perineural invasion-mediated inflammation in tumor microenvironment
por: Li, Xunjun, et al.
Publicado: (2023)

Tumor Immune Microenvironments (TIMEs): Responsive Nanoplatforms for Antitumor Immunotherapy
por: Sui, Xueqing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vgcac48bi7fvcacsenqdffu5dm