Quantum chemical investigation of predominant conformation of the antibiotic azithromycin in water and DMSO solutions: thermodynamic and NMR analysis

Azithromycin (AZM) is a macrolide-type antibiotic used to prevent and treat serious infections (mycobacteria or MAC) that significantly inhibit bacterial growth. Knowledge of the predominant conformation in solution is of fundamental importance for advancing our understanding of the intermolecular i...

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Detalles Bibliográficos
Autores principales: Hernandes, Isabel S., Da Silva, Haroldo C., Dos Santos, Hélio F., Ávila, Eloah P., De Almeida, Mauro V., De Almeida, Wagner B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565400/
https://www.ncbi.nlm.nih.gov/pubmed/37830015
http://dx.doi.org/10.1098/rsos.230409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565400/
https://www.ncbi.nlm.nih.gov/pubmed/37830015
http://dx.doi.org/10.1098/rsos.230409

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