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A tumour-spheroid manufacturing and cryopreservation process that yields a highly reproducible product ready for direct use in drug screening assays

If it were possible to purchase tumour-spheroids as a standardised product, ready for direct use in assays, this may contribute to greater research reproducibility, potentially reducing costs and accelerating outcomes. Herein, we describe a workflow where uniformly sized cancer tumour-spheroids are...

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Detalles Bibliográficos
Autores principales: Shajib, Md. Shafiullah, Futrega, Kathryn, Davies, Anthony M., Franco, Rose Ann G., McKenna, Eamonn, Guillesser, Bianca, Klein, Travis J., Crawford, Ross W., Doran, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565407/
https://www.ncbi.nlm.nih.gov/pubmed/37817581
http://dx.doi.org/10.1098/rsif.2023.0468