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Optimization of the dosage regimen of zoledronic acid with a kinetic-pharmacodynamic model and exposure-response analysis

Purpose: In order to support the dose optimization of zoledronic acid, the kinetic-pharmacodynamic model and exposure-response analysis were used to describe the changes in bone mineral density in different doses of zoledronic acid and establish the relationship between dose and acute phase reaction...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Liu, Qi, Jiang, Muhan, Song, Chunli, Liu, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565503/
https://www.ncbi.nlm.nih.gov/pubmed/37829305
http://dx.doi.org/10.3389/fphar.2023.1089774

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